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• Research PaperVolume 18, Issue 1pp 67-81

  P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts

  Relevance score: 0.00

  Shan Zhu, Jennifer Q Zhou, Kan Wang, Ming-lei Guo, Yan Y Sanders

  Keywords: senescence, fibroblast activation, p38 MAPK, lung fibrosis, H4K16Ac

  Published in Aging on March 3, 2026

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• Research PaperVolume 17, Issue 8pp 2033-2062

  The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity

  Relevance score: 0.00

  Abhishek Guha, Ying Si, Reed Smith, Brijesh K. Singh, Benisa Zogu, Angad Yadav, Katherine A. Smith, Mohamed Kazamel, Nan Jiang, Ritchie Ho, Anna Thalacker-Mercer, Shaida A. Andrabi, Joao D. Tavares Da Silva Pereira, Juliana S. Salgado, Manasi Agrawal, Emina Horvat Velic, Peter H. King

  Keywords: fibroblast growth factor 21, β-Klotho, ALS biomarker, human skeletal muscle, motor neurons

  Published in Aging on August 9, 2025

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• Research PaperVolume 16, Issue 19pp 12673-12684

  Fibroblast growth factor 21 inversely correlates with survival in elderly population – the results of the Polsenior2 study

  Relevance score: 0.00

  Gabriela Handzlik, Aleksander J. Owczarek, Andrzej Więcek, Małgorzata Mossakowska, Tomasz Zdrojewski, Anna Chudek, Magdalena Olszanecka-Glinianowicz, Jerzy Chudek

  Keywords: fibroblast growth factor 21, aging, survival, population-based study, longevity

  Published in Aging on September 18, 2024

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• Research PaperVolume 15, Issue 9pp 3738-3758

  Comprehensive analysis of the oncogenic and immunological role of FAP and identification of the ceRNA network in human cancers

  Relevance score: 0.00

  Weiqian Mai, Qingyou Liu, Jiasheng Li, Mincheng Zheng, Fuman Yan, Hui Liu, Yuhe Lei, Jinwen Xu, Jiean Xu

  Keywords: fibroblast activation protein-alpha (FAP), prognosis, immunological infiltration, competing endogenous RNA (ceRNA)

  Published in Aging on May 9, 2023

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• Research PaperVolume 14, Issue 17pp 6957-6974

  Integrated PPI- and WGCNA-retrieval of hub gene signatures for soft substrates inhibition of human fibroblasts proliferation and differentiation

  Relevance score: 0.00

  Ziran Xu, Tian Zhou, Yin Wang, Leijie Zhu, Jihao Tu, Zhixiang Xu, Lisha Li, Yulin Li

  Keywords: soft substrates, fibroblasts, proliferation, PPI, WGCNA

  Published in Aging on September 2, 2022

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• Research PaperVolume 13, Issue 14pp 18464-18481

  Fibroblastic galectin-1-fostered invasion and metastasis are mediated by TGF-β1-induced epithelial-mesenchymal transition in gastric cancer

  Relevance score: 0.00

  Xiaolan You, Jian Wu, Xiaojun Zhao, Xingyu Jiang, Wenxuan Tao, Zhiyi Chen, Chuanjiang Huang, Tingrui Zheng, Xianhe Shen

  Keywords: galectin-1, gastric cancer microenvironment, cancer-associated fibroblasts, epithelial-mesenchymal transition, TGF-β1/Smad signaling pathway

  Published in Aging on July 14, 2021

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• Research PaperVolume 13, Issue 10pp 13693-13707

  PDGFR-β⁺ fibroblasts deteriorate survival in human solid tumors: a meta-analysis

  Relevance score: 0.00

  Guoming Hu, Liming Huang, Kefang zhong, Liwei Meng, Feng Xu, Shimin Wang, Tao Zhang

  Keywords: tumor-infiltrating PDGFR-β+ fibroblasts, worse prognosis, solid tumor, meta-analysis

  Published in Aging on May 3, 2021

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• Research PaperVolume 13, Issue 4pp 4946-4961

  Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome

  Relevance score: 0.00

  Hisaya Kato, Yoshiro Maezawa, Naoya Takayama, Yasuo Ouchi, Hiyori Kaneko, Daisuke Kinoshita, Aki Takada-Watanabe, Motohiko Oshima, Masaya Koshizaka, Hideyuki Ogata, Yoshitaka Kubota, Nobuyuki Mitsukawa, Koji Eto, Atsushi Iwama, Koutaro Yokote

  Keywords: Werner syndrome, dermal fibroblasts, adipogenesis, chondrogenesis, osteogenesis

  Published in Aging on February 24, 2021

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• Research PaperVolume 13, Issue 2pp 2982-3009

  Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome

  Relevance score: 0.00

  Huixin Hao, Siyuan Ma, Cankun Zheng, Qiancheng Wang, Hairuo Lin, Zhenhuan Chen, Jiahe Xie, Lin Chen, Kaitong Chen, Yuegang Wang, Xiaobo Huang, Shiping Cao, Wangjun Liao, Jianping Bin, Yulin Liao

  Keywords: fibroblast growth factor 23, myocardial infarction, cardiorenal dysfunction, fibrosis

  Published in Aging on January 15, 2021

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• Research PaperVolume 12, Issue 14pp 14376-14390

  MicroRNA-15a/16/SOX5 axis promotes migration, invasion and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes

  Relevance score: 0.00

  Hua Wei, Qin Wu, Yumeng Shi, Aishu Luo, Shiyu Lin, Xiaoke Feng, Jintao Jiang, Miaojia Zhang, Fang Wang, Wenfeng Tan

  Keywords: rheumatoid arthritis, miR-15a/16, SOX5, fibroblast-like synoviocytes

  Published in Aging on July 17, 2020

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• Research PaperVolume 12, Issue 11pp 10951-10968

  Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury

  Relevance score: 0.00

  Sisi Li, Yechen Lu, Daofang Ding, Zhenzhen Ma, Xiangxin Xing, Xuyun Hua, Jianguang Xu

  Keywords: salidroside, fibroblast growth factors, dendrite, synaptic plasticity, stroke

  Published in Aging on June 9, 2020

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• EditorialVolume 11, Issue 4pp 1081-1082

  Parkinson’s disease as a systemic pathology

  Relevance score: 0.00

  Mario Ezquerra, María-José Martí, Rubén Fernández-Santiago

  Keywords: fibroblasts, Parkinson’s disease, transcriptomic

  Published in Aging on February 11, 2019

• Research PaperVolume 8, Issue 5pp 841-847

  Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan

  Relevance score: 0.00

  Alison Patrick, Michael Seluanov, Chaewon Hwang, Jonathan Tam, Tanya Khan, Ari Morgenstern, Lauren Wiener, Juan M. M. Vazquez, Hiba Zafar, Robert Wen, Malika Muratkalyeva, Katherine Doerig, Maria Zagorulya, Lauren Cole, Sophia Catalano, Aliny AB AB Lobo Ladd, A. Augusto Augusto Coppi, Yüksel Coşkun, Xiao Tian, Julia Ablaeva, Eviatar Nevo, Vadim N. N. Gladyshev, Zhengdong D. D. Zhang, Jan Vijg, Andrei Seluanov, Vera Gorbunova

  Keywords: fibroblasts, oxygen, senescence, human, rodents

  Published in Aging on May 7, 2016

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• Research PerspectiveVolume 3, Issue 10pp 920-933

  Roles of FGF signaling in stem cell self-renewal, senescence and aging

  Relevance score: 0.00

  Daniel L. Coutu, Jacques Galipeau

  Keywords: fibroblast growth factor, self-renewal, senescence, aging, adult stem cells, embryonic stem cells

  Published in Aging on October 9, 2011

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• Research PerspectiveVolume 1, Issue 12pp 1023-1027

  Role of FGF19 induced FGFR4 activation in the regulation of glucose homeostasis

  Relevance score: 0.00

  Xinle Wu, Yang Li

  Keywords: fibroblast growth factors, FGF19, FGF21, FGF23, aging, diabetes, metabolic diseases, insulin

  Published in Aging on December 9, 2009

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• Research PaperVolume 11, Issue 13pp 4536-4546

  Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging

  Relevance score: 0.00

  Vadim Zorin, Anna Grekhova, Margarita Pustovalova, Alla Zorina, Nadezhda Smetanina, Natalia Vorobyeva, Pavel Kopnin, Ilmira Gilmutdinova, Alexey Moskalev, Andreyan N. Osipov, Sergey Leonov

  Keywords: dermal fibroblasts, aging, γH2AX foci, proliferation, cellular senescence, β‐galactosidase, сlonogenic assay

  Published in Aging on July 9, 2019

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• Research PaperVolume 9, Issue 5pp 1404-1413

  Diffuse colonies of human skin fibroblasts in relation to cellular senescence and proliferation

  Relevance score: 0.00

  Vadim Zorin, Alla Zorina, Nadezhda Smetanina, Pavel Kopnin, Ivan V. Ozerov, Sergey Leonov, Artur Isaev, Dmitry Klokov, Andreyan N. Osipov

  Keywords: skin fibroblasts, сlonogenic assay, proliferation, cellular senescence, β-galactosidase

  Published in Aging on May 16, 2017

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• Research PaperVolume 7, Issue 2pp 110-122

  Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

  Relevance score: 0.00

  Faiza Kalfalah, Sabine Seggewiß, Regina Walter, Julia Tigges, María Moreno-Villanueva, Alexander Bürkle, Sebastian Ohse, Hauke Busch, Melanie Boerries, Barbara Hildebrandt, Brigitte Royer-Pokora, Fritz Boege

  Keywords: Aging, dermal fibroblasts, alkaline DNA unwinding, DNA double strand break repair, chromosome abnormalities, non-homologous end-joining

  Published in Aging on February 4, 2015

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• Research PaperVolume 1, Issue 9pp 784-802

  Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS)

  Relevance score: 0.00

  Ching-Chyuan Hsieh, John Papaconstantinou

  Keywords: dermal fibroblasts, mitochondrial ROS, rotenone, 3-nitropropionic acid, antimycin A, thioredoxin, ASK1, p38 MAPK, resistance to ROS, Ames dwarf mouse, aging

  Published in Aging on July 31, 2009

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• Research PaperVolume 16, Issue 18pp 12525-12542

  Revealing a cancer-associated fibroblast-based risk signature for pancreatic adenocarcinoma through single-cell and bulk RNA-seq analysis

  Relevance score: 0.00

  Jing Ma, Zhinan Chen, Limin Hou

  Keywords: cancer-associated fibroblasts, pancreatic adenocarcinoma, risk signature, immunotherapy, nomogram

  Published in Aging on September 26, 2024

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