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• Research PaperVolume 18, Issue 1pp 262-281

  Modeling premature aging in yeast via the expression of Progerin

  Relevance score: 0.00

  Zachery R. Belak, Christopher Ptak, Rachel E. Harris, Rick Wozniak, Christopher H. Eskiw, Troy AA. Harkness

  Keywords: Hutchinson-Gilford Progeria Syndrome, yeast, Progerin, Lamin A, premature aging

  Published in Aging on April 3, 2026

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• Research PaperVolume 17, Issue 9pp 2278-2311

  Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis

  Relevance score: 0.00

  Felix Quirin Fenzl, Eva-Maria Lederer, Louisa Brumma, Peter Krüger, Moritz Schroll, Frederic Wilming, Karima Djabali

  Keywords: aging, Hutchinson-Gilford progeria syndrome (HGPS), progerin, microRNAs, adipogenesis

  Published in Aging on August 27, 2025

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• Research PaperVolume 17, Issue 7pp 1667-1678

  National survey of Hutchinson-Gilford progeria syndrome and progeroid laminopathy in Japan

  Relevance score: 0.00

  Yuko Okawa, Muneaki Matsuo, Rika Kosaki, Hidefumi Tonoki, Masanobu Fujimoto, Keiichi Ozono, Hiroyuki Saitou, Takuo Kubota, Yasuhisa Ohata, Noriyuki Namba, Shinjiro Akaboshi, Hirofumi Komaki, Natsuko Inagaki, Eiko Kato, Yoshihiro Maruo, Takahiro Yonekawa, Tomomi Nakamura, Katsuhiro Hayashi, Shinji Miwa, Miyuki Magota, Kenji Ihara

  Keywords: Hutchinson-Gilford progeria syndrome, processing-deficient progeroid laminopathies, ZMPSTE24 gene, LMNA gene, progerin

  Published in Aging on July 9, 2025

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• Research PaperVolume 14, Issue 1pp 195-224

  Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria

  Relevance score: 0.00

  Christina Manakanatas, Santhosh Kumar Ghadge, Azra Agic, Fatih Sarigol, Petra Fichtinger, Irmgard Fischer, Roland Foisner, Selma Osmanagic-Myers

  Keywords: Hutchinson-Gilford progeria syndrome, cardiovascular disease, endothelial senescence, senescence-associated micro RNAs

  Published in Aging on January 12, 2022

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• Research PaperVolume 10, Issue 11pp 3148-3160

  BK channel overexpression on plasma membrane of fibroblasts from Hutchinson-Gilford progeria syndrome

  Relevance score: 0.00

  Isabella Zironi, Entelë Gavoçi, Giovanna Lattanzi, Angela Virelli, Fabrizio Amorini, Daniel Remondini, Gastone Castellani

  Keywords: Hutchinson-Gilford Progeria Syndrome (HGPS), gene LMNA, aging, patch clamp, membrane channels, K current ⁺, cellular proliferation

  Published in Aging on November 6, 2018

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• Research PerspectiveVolume 3, Issue 9pp 889-895

  Accelerated aging syndromes, are they relevant to normal human aging?

  Relevance score: 0.00

  Oliver Dreesen, Colin L. Stewart

  Keywords: Aging, Hutchinson-Gilford Progeria, Werner syndrome, DNA damage, telomeres, Wnt signaling, Lef1

  Published in Aging on September 14, 2011

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• EditorialVolume 13, Issue 12pp 15697-15698

  The pursuit of therapy for progeria

  Relevance score: 0.00

  Saurabh Saxena, Dhananjay Shukla

  Keywords: aging, Hutchinson-Gilford Progeria Syndrome, therapeutics

  Published in Aging on June 27, 2021

• EditorialVolume 12, Issue 6pp 4682-4684

  Nuclear protein export pathway in aging therapeutics

  Relevance score: 0.00

  Bulmaro Cisneros, Ian García-Aguirre

  Keywords: aging, Hutchinson-Gilford progeria syndrome, progerin, nuclear protein export, CRM1, selinexor

  Published in Aging on March 19, 2020

• Research PaperVolume 10, Issue 7pp 1758-1775

  Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

  Relevance score: 0.00

  Steve Horvath, Junko Oshima, George M. Martin, Ake T. Lu, Austin Quach, Howard Cohen, Sarah Felton, Mieko Matsuyama, Donna Lowe, Sylwia Kabacik, James G. Wilson, Alex P. Reiner, Anna Maierhofer, Julia Flunkert, Abraham Aviv, Lifang Hou, Andrea A. Baccarelli, Yun Li, James D. Stewart, Eric A. Whitsel, Luigi Ferrucci, Shigemi Matsuyama, Kenneth Raj

  Keywords: epigenetics, fibroblasts, DNA methylation, progeria, Hutchinson-Gilford

  Published in Aging on July 26, 2018

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• Research PaperVolume 8, Issue 2pp 366-381

  Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase

  Relevance score: 0.00

  Olga Moiseeva, Stéphane Lopes-Paciencia, Geneviève Huot, Frédéric Lessard, Gerardo Ferbeyre

  Keywords: lamin A, cyclin dependent kinases, senescence, liquid droplets, Hutchinson-Gilford progeria syndrome

  Published in Aging on February 21, 2016

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• ReviewVolume 1, Issue 1pp 28-37

  Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

  Relevance score: 0.00

  Phillip R. Musich, Yue Zou

  Keywords: Lamin A, Hutchinson-Gilford progeria syndrome, premature aging, Genome instability, DNA damage responses, XPA, DNA double strand breaks, DNA repair

  Published in Aging on January 16, 2009

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• Research PaperVolume 6, Issue 12pp 1049-1063

  Progerin expression disrupts critical adult stem cell functions involved in tissue repair

  Relevance score: 0.00

  Laurin Marie Pacheco, Lourdes Adriana Gomez, Janice Dias, Noel M Ziebarth, Guy A Howard, Paul C Schiller

  Keywords: aging, progerin, HGPS, Hutchinson-Gilford Progeria Syndrome, Progeria, MSC

  Published in Aging on December 21, 2014

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• Research PaperVolume 3, Issue 4pp 380-390

  Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C

  Relevance score: 0.00

  Jenny CY Ho, Ting Zhou, Wing-Hon Lai, Yinghua Huang, Yau-Chi Chan, Xingyan Li, Navy LY Wong, Yanhua Li, Ka-Wing Au, Dongsheng Guo, Jianyong Xu, Chung-Wah Siu, Duanqing Pei, Hung-Fat Tse, Miguel Angel Esteban

  Keywords: reprogramming, induced pluripotent stem cells, lamin A/C, dilated cardiomyopathy, atypical Werner syndrome, Hutchinson Gilford progeria

  Published in Aging on March 28, 2011

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