Special Collection on p53 Part 2

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Integrated analysis of colorectal cancer microRNA datasets: identification of microRNAs associated with tumor development

Luca Falzone, Letizia Scola, Antonino Zanghì, Antonio Biondi, Antonio Di Cataldo, Massimo Libra, Saverio Candido

https://doi.org/10.18632/aging.101444pp 1000—1014

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Is MDMX the better target?

Ning Kon, Wei Gu

https://doi.org/10.18632/aging.101479pp 1184—1185

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ZNF185 is a p53 target gene following DNA damage

Artem Smirnov, Angela Cappello, Anna Maria Lena, Lucia Anemona, Alessandro Mauriello, Nicola Di Daniele, Margherita Annicchiarico-Petruzzelli, Gerry Melino, Eleonora Candi

https://doi.org/10.18632/aging.101639pp 3308—3326

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TAp73 regulates ATP7A: possible implications for ageing-related diseases

Piervito Lopriore, Nazzareno Capitanio, Emanuele Panatta, Nicola Di Daniele, Alessandra Gambacurta, Gerry Melino, Ivano Amelio

https://doi.org/10.18632/aging.101669pp 3745—3760

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ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma

Valentina Frezza, Claudia Fierro, Elena Gatti, Angelo Peschiaroli, Anna Maria Lena, Margherita Annicchiarico Petruzzelli, Eleonora Candi, Lucia Anemona, Alessandro Mauriello, Pier Giuseppe Pelicci, Gerry Melino, Francesca Bernassola

https://doi.org/10.18632/aging.101725pp 4224—4240

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Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging

Zsofia Turi, Matthew Lacey, Martin Mistrik, Pavel Moudry

https://doi.org/10.18632/aging.101922pp 2512—2540

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Overexpressed methyltransferase-like 1 (METTL1) increased chemosensitivity of colon cancer cells to cisplatin by regulating miR-149-3p/S100A4/p53 axis

Yang Liu, Chunyan Yang, Yong Zhao, Qiang Chi, Zhen Wang, Boshi Sun

https://doi.org/10.18632/aging.102575pp 12328—12344

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TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer

Shaw M. Akula, Peter P. Ruvolo, James A. McCubrey

https://doi.org/10.18632/aging.102776pp 2777—2797

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CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis

Qiuhua Lai, Qingyuan Li, Chengcheng He, Yuxin Fang, Simin Lin, Jianqun Cai, Jian Ding, Qian Zhong, Yue Zhang, Changjie Wu, Xinke Wang, Juan He, Yongfeng Liu, Qun Yan, Aimin Li, Side Liu

https://doi.org/10.18632/aging.103648pp 16270—16293

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Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation

Tingting Zheng, Keke Chen, Xue Zhang, Huanhuan Feng, Yu Shi, Li Liu, Jun Zhang, Yun Chen

https://doi.org/10.18632/aging.103915pp 18649—18659

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p21 can be a barrier to ferroptosis independent of p53

Divya Venkatesh, Brent R. Stockwell, Carol Prives

https://doi.org/10.18632/aging.103961pp 17800—17814

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Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE₂ pathway in non-small cell lung cancer

Minghui Zhao, Yiwei Wang, Yucui Zhao, Sijia He, Ruyi Zhao, Yanwei Song, Jin Cheng, Yanping Gong, Jianzhu Xie, Yulan Wang, Binjie Hu, Ling Tian, Qian Huang

https://doi.org/10.18632/aging.103984pp 21758—21776

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Overexpression of hsa_circ_0002874 promotes resistance of non-small cell lung cancer to paclitaxel by modulating miR-1273f/MDM2/p53 pathway

Jianhao Xu, Liwei Ni, Fenglun Zhao, Xiaoxiao Dai, Jialong Tao, Jia Pan, Aiming Shi, Zhu Shen, Cunjin Su, Yusong Zhang

https://doi.org/10.18632/aging.202521pp 5986—6009

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ITPKA induces cell senescence, inhibits ovarian cancer tumorigenesis and can be downregulated by miR-203

Wang Shaosheng, Wang Shaochuang, Fan Lichun, Xie Na, Zhao Xiaohong

https://doi.org/10.18632/aging.202880pp 11822—11832

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Expression profile, molecular functions, and prognostic significance of miRNAs in primary colorectal cancer stem cells

Chuan-Wen Fan, Ran Lu, Chao Fang, Xue-Li Zhang, Zhao-Ying Lv, Yuan Li, Hong Zhang, Zong-Guang Zhou, Xian-Ming Mo, Xiao-Feng Sun

https://doi.org/10.18632/aging.202914pp 12067—12085

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Cdkn1a transcript variant 2 is a marker of aging and cellular senescence

José Alberto López-Domínguez, Sandra Rodríguez-López, Ulises Ahumada-Castro, Pierre-Yves Desprez, Maria Konovalenko, Remi-Martin Laberge, César Cárdenas, José Manuel Villalba, Judith Campisi

https://doi.org/10.18632/aging.203110pp 13380—13392

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LHX9, a p53-binding protein, inhibits the progression of glioma by suppressing glycolysis

Xiangying Luo, Jianwei Ge, Tao Chen, Jinfang Liu, Ziyuan Liu, Changlong Bi, Song Lan

https://doi.org/10.18632/aging.203436pp 22109—22119

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Metformin-induced chemosensitization to cisplatin depends on P53 status and is inhibited by Jarid1b overexpression in non-small cell lung cancer cells

Tharcisio Citrangulo Tortelli Jr, Rodrigo Esaki Tamura, Mara de Souza Junqueira, Janio da Silva Mororó, Silvina Odete Bustos, Renato Jose Mendonça Natalino, Shonagh Russell, Laurent Désaubry, Bryan Eric Strauss, Roger Chammas

https://doi.org/10.18632/aging.203528pp 21914—21940

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The telomere-mitochondrial axis of aging in newborns

Charlotte Van Der Stukken, Tim S. Nawrot, Rossella Alfano, Congrong Wang, Sabine A.S. Langie, Michelle Plusquin, Bram G. Janssen, Dries S. Martens

https://doi.org/10.18632/aging.203897pp 1627—1650

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TP53/BRAF mutation as an aid in predicting response to immune-checkpoint inhibitor across multiple cancer types

Jia-Zheng Cao, Gao-Sheng Yao, Fei Liu, Yi-Ming Tang, Peng-Ju Li, Zi-Hao Feng, Jun-Hang Luo, Jin-Huan Wei

https://doi.org/10.18632/aging.203980pp 2868—2879

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Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties

James A. McCubrey, Akshaya K. Meher, Shaw M. Akula, Stephen L. Abrams, Linda S. Steelman, Michelle M. LaHair, Richard A. Franklin, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Fulvio Barbaro, Przemysław Duda, Agnieszka Gizak

https://doi.org/10.18632/aging.204038pp 3365—3386

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