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• Research PaperVolume 13, Issue 15pp 19598-19613

  Computational research of mTORC1 inhibitor on cerebral ischemia-reperfusion injury

  Relevance score: 0.00

  Hui Li, Wenzhuo Yang, Zhenhua Wang, Xu Wang, Yulei Hao, Jianxin Xi, Han Lu, Zhishan Du, Jiachun Feng, Bao Zhang, Di Ma

  Keywords: cerebral ischemia/reperfusion injury (CIRI), the mammalian target of rapamycin (mTORC1), mTORC1 inhibitors, autophagy

  Published in Aging on August 3, 2021

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• Research PaperVolume 8, Issue 12pp 3535-3551

  Gerosuppression by pan-mTOR inhibitors

  Relevance score: 0.00

  Olga V. Leontieva, Mikhail V. Blagosklonny

  Keywords: dual mTORC1/C2 inhibitors, rapalogs, sirolimus, aging, cancer, senescence

  Published in Aging on December 30, 2016

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• Research PaperVolume 16, Issue 14pp 11134-11150

  mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease

  Relevance score: 0.00

  Karl Berner, Naci Oz, Alaattin Kaya, Animesh Acharjee, Jon Berner

  Keywords: ketamine, lithium, monocyte, mTORC1, rapamycin

  Published in Aging on July 26, 2024

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• Research PaperVolume 15, Issue 16pp 7933-7955

  A novel hepatocellular carcinoma-specific mTORC1-related signature for anticipating prognosis and immunotherapy

  Relevance score: 0.00

  Erbao Chen, Yuqian Mo, Jing Yi, Jie Liu, Ting Luo, Zheng Li, Zewei Lin, Yibing Hu, Zhilin Zou, Jikui Liu

  Keywords: mTORC1, tumor microenvironment, hepatocellular carcinoma, immunotherapy, prognosis

  Published in Aging on August 16, 2023

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• EditorialVolume 13, Issue 11pp 14544-14545

  mTORC1 is also involved in longevity between species

  Relevance score: 0.00

  Gustavo Barja, Reinald Pamplona

  Keywords: longevity, aging rate, Cell Aging Regulating System (CARS), nuclear aging program (AP), mTORC1 complex

  Published in Aging on May 29, 2021

• Research PaperVolume 11, Issue 19pp 8418-8432

  mTORC1-Sch9 regulates hydrogen sulfide production through the transsulfuration pathway

  Relevance score: 0.00

  Zhou Lyu, Xuejie Gao, Weiyan Wang, Jinye Dang, Li Yang, Mengli Yan, Shah Arman Ali, Yang Liu, Binghua Liu, Meng Yu, Linfang Du, Ke Liu

  Keywords: hydrogen sulfide, Sch9, mTORC1, cystathionine gamma-lyase, cystathionine beta-synthase

  Published in Aging on October 3, 2019

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• EditorialVolume 9, Issue 7pp 1641-1642

  Amino acid metabolites, mTORC1 and aging

  Relevance score: 0.00

  Henri Antikainen, Khoosheh Khayati, Radek Dobrowolski

  Keywords: mTORC1, autophagy, aging, amino acid, metabolites

  Published in Aging on July 17, 2017

• EditorialVolume 8, Issue 6pp 1165-1166

  mTORC1 regulates nutrient access in Ras-mediated tumors

  Relevance score: 0.00

  Heesun Cheong

  Keywords: mTORC1, autophagy, macropinocytosis, Ras

  Published in Aging on June 9, 2016

• Research PaperVolume 12, Issue 13pp 13023-13037

  The Gαh/phospholipase C-δ1 interaction promotes autophagosome degradation by activating the Akt/mTORC1 pathway in metastatic triple-negative breast cancer

  Relevance score: 0.00

  Hui-Yu Lin, Chia-Hao Kuei, Hsun-Hua Lee, Che-Hsuan Lin, Jing-Quan Zheng, Hui-Wen Chiu, Chi-Long Chen, Yuan-Feng Lin

  Keywords: gαh, autophagy, Akt/mTORC1, metastasis, triple-negative breast cancer

  Published in Aging on July 1, 2020

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• EditorialVolume 9, Issue 8pp 1851-1852

  Dysregulation of mTORC1/autophagy axis in senescence

  Relevance score: 0.00

  Bernadette Carroll, Viktor I. Korolchuk

  Keywords: senescence, mTORC1, autophagy

  Published in Aging on August 5, 2017

• Research PaperVolume 13, Issue 18pp 22412-22431

  Pim-2 kinase inhibits inflammation by suppressing the mTORC1 pathway in atherosclerosis

  Relevance score: 0.00

  Minqi Liao, Feng Hu, Zhiqiang Qiu, Juan Li, Chahua Huang, Yan Xu, Xiaoshu Cheng

  Keywords: Pim-2, atherosclerosis, inflammatory, mTORC1

  Published in Aging on September 21, 2021

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• EditorialVolume 11, Issue 16pp 5868-5870

  Rapamycin protects aging muscle

  Relevance score: 0.00

  Huibin Tang, Joseph B. Shrager, Daniel Goldman

  Keywords: rapamycin, mTORC1, aging, skeletal muscle, oxidative stress

  Published in Aging on August 27, 2019

• Research PaperVolume 10, Issue 4pp 658-673

  Physical decline and survival in the elderly are affected by the genetic variability of amino acid transporter genes

  Relevance score: 0.00

  Paolina Crocco, Eneida Hoxha, Serena Dato, Francesco De Rango, Alberto Montesanto, Giuseppina Rose, Giuseppe Passarino

  Keywords: amino acid transporter genes, mTORC1, aging, muscle decline, sarcopenia, Hand grip, ADL

  Published in Aging on April 18, 2018

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• Research PaperVolume 9, Issue 4pp 1326-1340

  BMP2 promotes proliferation and invasion of nasopharyngeal carcinoma cells via mTORC1 pathway

  Relevance score: 0.00

  Meng-He Wang, Xiao-Min Zhou, Mei-Yin Zhang, Lu Shi, Ruo-Wen Xiao, Li-Si Zeng, Xian-Zi Yang, X.F. Steven Zheng, Hui-Yun Wang, Shi-Juan Mai

  Keywords: nasopharyngeal carcinoma, BMP2, metastasis, mTORC1

  Published in Aging on April 28, 2017

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• Research PaperVolume 16, Issue 19pp 12866-12892

  DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway

  Relevance score: 0.00

  Ting Zheng, Ding Zhang, Qingzhen Fu, Mingxue Wang, Zesong Cheng, Yukun Cao, Liwan Wang, Jinyin Liu, Yashuang Zhao

  Keywords: colorectal cancer, methylation-driven gene, FAM3D, mTORC1 pathway, prognostic marker

  Published in Aging on October 10, 2024

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• Research PaperVolume 11, Issue 23pp 11520-11540

  Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes

  Relevance score: 0.00

  Qi Peng, Bin Chen, Hao Wang, Ying Zhu, Jinghong Wu, Yetao Luo, Guowei Zuo, Jinyong Luo, Lan Zhou, Qiong Shi, Yaguang Weng, Ailong Huang, Tong-Chuan He, Jiaming Fan

  Keywords: non-alcoholic fatty liver disease (NAFLD), hepatic lipid metabolism, BMP signaling, mTORC1 signaling

  Published in Aging on December 12, 2019

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• Research PaperVolume 8, Issue 2pp 231-244

  Reversal of phenotypes of cellular senescence by pan-mTOR inhibition

  Relevance score: 0.00

  Hannah E. Walters, Sylwia Deneka-Hannemann, Lynne S. Cox

  Keywords: cellular senescence, aging, mTORC1, mTORC2, rapamycin, AZD8055

  Published in Aging on February 5, 2016

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