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Volume 10, Issue 4

April 2018pp 516—852

About the Cover

The cover for issue 4 of Aging features Figure 6 "Differentially expressed genes (DEGs) and pathways in aged female vs. aged male" from Wang et al.

Editorials

The memory remains

Matthias Altmeyer

https://doi.org/10.18632/aging.101408pp 516—517

Gene therapy for p16-overexpressing cells

Marco Demaria

https://doi.org/10.18632/aging.101422pp 518—519

Chronotherapy with defective circadian clock?

Yuan Zhang, Francis Lévi, Yunhua Chang

https://doi.org/10.18632/aging.101430pp 520—521

Swiprosin-1/EFhd2 – another piece in the puzzle of tauopathy?

Martin Regensburger, Dirk Mielenz, Beate Winner

https://doi.org/10.18632/aging.101431pp 522—523

Age-related neuropathies and tubulin acetylation

Jaime Fernández-Barrera, Isabel Correas, Miguel A. Alonso

https://doi.org/10.18632/aging.101432pp 524—525

Decreased NAD+ in dopaminergic neurons

Samantha L. Sison, Allison D. Ebert

https://doi.org/10.18632/aging.101433pp 526—527

Phospholipid transfer by ERMES components

Toshiya Endo, Yasushi Tamura, Shin Kawano

https://doi.org/10.18632/aging.101434pp 528—529

Accessory signals in protein translocation

Katja G. Hansen, Felix Boos, Johannes M. Herrmann

https://doi.org/10.18632/aging.101435pp 530—531

Research Papers

A net-shaped multicellular formation facilitates the maturation of hPSC-derived cardiomyocytes through mechanical and electrophysiological stimuli

Taoyan Liu, Chengwu Huang, Hongxia Li, Fujian Wu, Jianwen Luo, Wenjing Lu, Feng Lan

https://doi.org/10.18632/aging.101411pp 532—548

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Unrepaired DNA damage in macrophages causes elevation of particulate matter- induced airway inflammatory response

Man Luo, Zhengqiang Bao, Feng Xu, Xiaohui Wang, Fei Li, Wen Li, Zhihua Chen, Songmin Ying, Huahao Shen

https://doi.org/10.18632/aging.101412pp 549—560

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The evolution of CpG density and lifespan in conserved primate and mammalian promoters

Adam T. McLain, Christopher Faulk

https://doi.org/10.18632/aging.101413pp 561—572

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An epigenetic biomarker of aging for lifespan and healthspan

Morgan E. Levine, Ake T. Lu, Austin Quach, Brian H. Chen, Themistocles L. Assimes, Stefania Bandinelli, Lifang Hou, Andrea A. Baccarelli, James D. Stewart, Yun Li, Eric A. Whitsel, James G Wilson, Alex P Reiner, Abraham Aviv, Kurt Lohman, Yongmei Liu, Luigi Ferrucci, Steve Horvath

https://doi.org/10.18632/aging.101414pp 573—591

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Mining TCGA database for genes of prognostic value in glioblastoma microenvironment

Di Jia, Shenglan Li, Dali Li, Haipeng Xue, Dan Yang, Ying Liu

https://doi.org/10.18632/aging.101415pp 592—605

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Sex differences in transcriptomic profiles in aged kidney cells of renin lineage

Yuliang Wang, Diana G. Eng, Jeffrey W. Pippin, Sina A. Gharib, Aaron McClelland, Kenneth W. Gross, Stuart J. Shankland

https://doi.org/10.18632/aging.101416pp 606—621

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Stress resistance and lifespan enhanced by downregulation of antimicrobial peptide genes in the Imd pathway

Yuh-Ru Lin, Hardik Parikh, Yongkyu Park

https://doi.org/10.18632/aging.101417pp 622—631

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KCNQ1OT1 promotes melanoma growth and metastasis

Bingyu Guo, Qian Zhang, Hongyi Wang, Peng Chang, Kai Tao

https://doi.org/10.18632/aging.101418pp 632—644

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AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation

Teng Jiang, Liu-Jun Xue, Yang Yang, Qing-Guang Wang, Xiao Xue, Zhou Ou, Qing Gao, Jian-Quan Shi, Liang Wu, Ying-Dong Zhang

https://doi.org/10.18632/aging.101419pp 645—657

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Physical decline and survival in the elderly are affected by the genetic variability of amino acid transporter genes

Paolina Crocco, Eneida Hoxha, Serena Dato, Francesco De Rango, Alberto Montesanto, Giuseppina Rose, Giuseppe Passarino

https://doi.org/10.18632/aging.101420pp 658—673

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Involvement of SPATA31 copy number variable genes in human lifespan

Cemalettin Bekpen, Chen Xie, Almut Nebel, Diethard Tautz

https://doi.org/10.18632/aging.101421pp 674—688

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Association of VAMP5 and MCC genetic polymorphisms with increased risk of Hirschsprung disease susceptibility in Southern Chinese children

Jinglu Zhao, Xiaoli Xie, Yuxiao Yao, Qiuming He, Ruizhong Zhang, Huimin Xia, Yan Zhang

https://doi.org/10.18632/aging.101423pp 689—700

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Transcriptional profiling identifies strain-specific effects of caloric restriction and opposite responses in human and mouse white adipose tissue

William R. Swindell, Edward O. List, Darlene E. Berryman, John J. Kopchick

https://doi.org/10.18632/aging.101424pp 701—746

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Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion

Hidetoshi Sugihara, Naomi Teramoto, Keitaro Yamanouchi, Takashi Matsuwaki, Masugi Nishihara

https://doi.org/10.18632/aging.101425pp 747—763

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Novel role of autophagy-associated Pik3c3 gene in gonadal white adipose tissue browning in aged C57/Bl6 male mice

Amiya Kumar Ghosh, Theresa Mau, Martin O’Brien, Raymond Yung

https://doi.org/10.18632/aging.101426pp 764—774

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Identifying circRNA-associated-ceRNA networks in the hippocampus of Aβ1-42-induced Alzheimer's disease-like rats using microarray analysis

Zhe Wang, Panpan Xu, Biyue Chen, Zheyu Zhang, Chunhu Zhang, Qiong Zhan, Siqi Huang, Zi-an Xia, Weijun Peng

https://doi.org/10.18632/aging.101427pp 775—788

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Age-associated bimodal transcriptional drift reduces intergenic disparities in transcription

Byungkuk Min, Myungsun Park, Kyuheum Jeon, Jung Sun Park, Hyemyung Seo, Sangkyun Jeong, Yong-Kook Kang

https://doi.org/10.18632/aging.101428pp 789—807

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RAN/RANBP2 polymorphisms and neuroblastoma risk in Chinese children: a three-center case-control study

Juxiang Wang, Zhenjian Zhuo, Min Chen, Jinhong Zhu, Jie Zhao, Jiao Zhang, Shanshan Chen, Jing He, Haixia Zhou

https://doi.org/10.18632/aging.101429pp 808—818

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Coherent apoptotic and autophagic activities involved in regression of chicken postovulatory follicles

Xin Lin, Xingting Liu, Yanfen Ma, Yuling Mi, Weidong Zeng, Jian Li, Caiqiao Zhang

https://doi.org/10.18632/aging.101436pp 819—832

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CircRNAs in the tree shrew (Tupaia belangeri) brain during postnatal development and aging

CaiXia Lu, XiaoMei Sun, Na Li, WenGuang Wang, DeXuan Kuang, PinFen Tong, YuanYuan Han, JieJie Dai

https://doi.org/10.18632/aging.101437pp 833—852

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