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• Research PaperVolume 11, Issue 13pp 4323-4337

  HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration

  Relevance score: 0.00

  Shuo Sun, Bincui Cai, Yao Li, Wenqi Su, Xuzheng Zhao, Boteng Gong, Zhiqing Li, Xiaomin Zhang, Yalin Wu, Chao Chen, Stephen H. Tsang, Jin Yang, Xiaorong Li

  Keywords: A2E, HMGB1, Caveolin-1, RPE cell senescence, AMD

  Published in Aging on July 7, 2019

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• EditorialVolume 16, Issue 12pp 10201-10202

  Aging retinal pigmented epithelium: omics-based insights into vision decline

  Relevance score: 0.00

  Ioan V. Matei, Luminita Paraoan

  Keywords: RPE, vision, aging, omics

  Published in Aging on June 12, 2024

• Research PaperVolume 5, Issue 1pp 51-66

  Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: A novel culture model for dry AMD

  Relevance score: 0.00

  David M. Rabin, Richard L. Rabin, Timothy A. Blenkinsop, Sally Temple, Jeffrey H. Stern

  Keywords: RPE, oxidative stress, AMD

  Published in Aging on December 20, 2012

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• Research PaperVolume 10, Issue 6pp 1306-1323

  Loss of NAMPT in aging retinal pigment epithelium reduces NAD⁺ availability and promotes cellular senescence

  Relevance score: 0.00

  Ravirajsinh N. Jadeja, Folami L. Powell, Malita A. Jones, Jasmine Fuller, Ethan Joseph, Menaka C. Thounaojam, Manuela Bartoli, Pamela M. Martin

  Keywords: retinal pigment epithelium (RPE), aging, age-related macular degeneration (AMD), NAD+, NAMPT, senescence, SIRT1

  Published in Aging on June 12, 2018

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• Research PaperVolume 13, Issue 18pp 22040-22058

  A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin

  Relevance score: 0.00

  Valérie Fontaine, Mylène Fournié, Elodie Monteiro, Thinhinane Boumedine, Christine Balducci, Louis Guibout, Mathilde Latil, José-Alain Sahel, Stanislas Veillet, Pierre J. Dilda, René Lafont, Serge Camelo

  Keywords: N-retinylidene-N-retinylethanolamine (A2E), norbixin, peroxisome proliferator-activated receptor (PPAR), retinal pigment epithelium (RPE), retinoic X receptor (RXR)

  Published in Aging on September 20, 2021

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• Research PaperVolume 15, Issue 9pp 3465-3479

  Palmitic acid–induced microRNA-143-5p expression promotes the epithelial–mesenchymal transition of retinal pigment epithelium via negatively regulating JDP2

  Relevance score: 0.00

  Yunlin Tian, Juan Shao, Shuwei Bai, Zhiguo Xu, Chunchao Bi

  Keywords: epithelial–mesenchymal transition (EMT), retinal pigment epithelial (RPE) cells, miR-143-5p, JDP2

  Published in Aging on April 25, 2023

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• Research PaperVolume 11, Issue 17pp 6691-6713

  PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

  Relevance score: 0.00

  Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

  Keywords: age-related macular degeneration (AMD), RPE, PGC-1α, mitochondria, FDA-approved drugs

  Published in Aging on September 2, 2019

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 12, Issue 10pp 9031-9040

  Role of Citicoline in an in vitro AMD model

  Relevance score: 0.00

  Sonali Nashine, M. Cristina Kenney

  Keywords: Citicoline, age-related macular degeneration (AMD), neuroprotection, RPE, mitochondria

  Published in Aging on May 29, 2020

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