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• Research PaperVolume 13, Issue 16pp 20246-20257

  Identification of effective natural PIK3CA H1047R inhibitors by computational study

  Relevance score: 0.00

  Naimeng Liu, Xinhui Wang, Xuan Li, Xiaye Lv, Haoqun Xie, Zhen Guo, Jing Wang, Gaojing Dou, Ye Du, Dong Song

  Keywords: PIK3CA H1047R, drug development, virtual screening, TNBC, targeted therapy

  Published in Aging on August 20, 2021

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• Research PaperVolume 12, Issue 2pp 1577-1590

  PIK3CA gene mutations in the helical domain correlate with high tumor mutation burden and poor prognosis in metastatic breast carcinomas with late-line therapies

  Relevance score: 0.00

  Yu Tang, Jing Li, Ning Xie, Xiaohong Yang, Liping Liu, Hui Wu, Can Tian, Ying He, Xiao Wang, Qiongzhi He, Zhe-Yu Hu, Quchang Ouyang

  Keywords: metastatic breast cancers, PIK3CA mutations, helical domain, tumor mutation burden, ctDNA mutation profile

  Published in Aging on January 24, 2020

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• Research PaperVolume 16, Issue 11pp 9410-9436

  APOA5 alleviates reactive oxygen species to promote oxaliplatin resistance in PIK3CA-mutated colorectal cancer

  Relevance score: 0.00

  Yu-Lin Liu, Zhuo Xiang, Bo-Ya Zhang, Yu-Wei Zou, Gui-Lai Chen, Li Yin, Yan-Long Shi, Li-Li Xu, Jingwang Bi, Qiang Wang

  Keywords: colorectal cancer, oxaliplatin resistance, PIK3CA mutation, apolipoprotein A5, reactive oxygen species

  Published in Aging on June 6, 2024

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• Research PaperVolume 11, Issue 11pp 3768-3784

  Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway

  Relevance score: 0.00

  Benrong Liu, Lin Wang, Wenyi Jiang, Yujuan Xiong, Lihua Pang, Yun Zhong, Chongyu Zhang, Wenchao Ou, Chaowei Tian, Xiaohui Chen, Shi-Ming Liu

  Keywords: myocyte enhancer factor 2A, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG), Sirtuin 1 (SIRT1), senescence

  Published in Aging on June 10, 2019

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