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• Research PaperVolume 13, Issue 14pp 18993-19012

  A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer’s disease mechanisms

  Relevance score: 0.00

  Peng Zeng, Meng Fang, Han Zhao, Jing Guo

  Keywords: Alzheimer’s disease, Ginkgo Folium, network pharmacology, genkwanin, AD pathology

  Published in Aging on July 27, 2021

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• Research PaperVolume 10, Issue 9pp 2316-2337

  The etiological effect of a new low-frequency ESR1 variant on Mild Cognitive Impairment and Alzheimer’s Disease: a population-based study

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  Xiaoling Li, Xiaoquan Zhu, Wandong Zhang, Fan Yang, Juan Hui, Jiping Tan, Haiqun Xie, Dantao Peng, Lihua Ma, Lianqi Cui, Shouzi Zhang, Zeping Lv, Liang Sun, Huiping Yuan, Qi Zhou, Luning Wang, Shige Qi, Zhihui Wang, Caiyou Hu, Ze Yang

  Keywords: AD, MCI, ESR1, cholesterol, Aβ

  Published in Aging on September 16, 2018

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• Research PaperVolume 16, Issue 3pp 1983-2004

  GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects

  Relevance score: 0.00

  Hyun-Hee Park, Hyuk Sung Kwon, Kyu-Yong Lee, Ye Eun Kim, Jeong-Woo Son, Na-Young Choi, Myung-Hoon Han, Dong Woo Park, Sangjae Kim, Seong-Ho Koh

  Keywords: 3xTg-AD mice, GV1001, neurodegeneration, anti-aging, Alzheimer’s disease

  Published in Aging on January 31, 2024

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• Research PaperVolume 14, Issue 19pp 8077-8094

  Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets

  Relevance score: 0.00

  Qian Guo, Gang Wu, Fang Huang, Zhen Wei, Jian-Zhi Wang, Bin Zhang, Rong Liu, Yang Yang, Xiaochuan Wang, Hong-Lian Li

  Keywords: Alzheimer’s disease (AD), Huperzine A (Hup-A), beta-secretase 1 (BACE1), protein phosphatase- 2A (PP2A), cholinesterase inhibitor

  Published in Aging on October 12, 2022

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• Research PaperVolume 12, Issue 3pp 2897-2920

  Identifying lncRNA–miRNA–mRNA networks to investigate Alzheimer’s disease pathogenesis and therapy strategy

  Relevance score: 0.00

  Nana Ma, Changrui Tie, Bo Yu, Wei Zhang, Jun Wan

  Keywords: Alzheimer’s disease (AD), ceRNA network, APP/PS1 mouse, RNA-sequencing, lncRNA

  Published in Aging on February 7, 2020

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• Research PaperVolume 15, Issue 17pp 9022-9040

  Causal relationship between Alzheimer’s disease and cardiovascular disease: a bidirectional Mendelian randomization analysis

  Relevance score: 0.00

  Fengjun Zhang, Dexian Xian, Junchen Feng, Luning Ning, Tianshou Jiang, Wenchang Xu, Yuan Liu, Qiong Zhao, Min Peng

  Keywords: Alzheimer's disease (AD), cardiovascular disease (CVD), causality, bidirectional mendelian randomization (MR) study, genome-wide association study (GWAS)

  Published in Aging on September 2, 2023

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• Research PaperVolume 13, Issue 11pp 14940-14967

  Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer’s disease

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  Tong Zhang, Yang Shen, Yiqing Guo, Junyan Yao

  Keywords: Alzheimer's disease (AD), β-amyloid (Aβ), phosphorylated tau (p-tau), gene module, transcriptome biomarker

  Published in Aging on May 24, 2021

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• Research PaperVolume 11, Issue 2pp 697-706

  Chronic hyperglycemia regulates microglia polarization through ERK5

  Relevance score: 0.00

  Congde Chen, Suichun Wu, Zipu Hong, Xiaoming Chen, Xiaoou Shan, Shane Fischbach, Xiangwei Xiao

  Keywords: extracellular-signal-regulated kinase 5 (ERK5), diabetes, Alzheimer’s disease (AD), microglia, polarization

  Published in Aging on January 26, 2019

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• Research PaperVolume 17, Issue 5pp 1105-1138

  APOE genotype and biological age impact inter-omic associations related to bioenergetics

  Relevance score: 0.00

  Dylan Ellis, Kengo Watanabe, Tomasz Wilmanski, Michael S. Lustgarten, Andres V. Ardisson Korat, Gwênlyn Glusman, Jennifer Hadlock, Oliver Fiehn, Paola Sebastiani, Nathan D. Price, Leroy Hood, Andrew T. Magis, Simon J. Evans, Lance Pflieger, Jennifer C. Lovejoy, Sean M. Gibbons, Cory C. Funk, Priyanka Baloni, Noa Rappaport

  Keywords: apolipoprotein E (APOE), biological age, metabolism, Alzheimer’s disease (AD), insulin resistance

  Published in Aging on May 3, 2025

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• Research PaperVolume 13, Issue 6pp 9011-9027

  Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing

  Relevance score: 0.00

  Kan He, Jian Zhang, Justin Liu, Yandi Cui, Leyna G. Liu, Shoudong Ye, Qian Ban, Ruolan Pan, Dahai Liu

  Keywords: PIAS1, HT-22, RNA-seq, pathway, AD

  Published in Aging on March 24, 2021

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• Research PaperVolume 11, Issue 18pp 7978-7995

  GSK-3β and ERK1/2 incongruously act in tau hyperphosphorylation in SPS-induced PTSD rats

  Relevance score: 0.00

  Zhen Wei, Yacoubou Abdoul Razak Mahaman, Feiqi Zhu, Mengjuan Wu, Yiyuan Xia, Kuan Zeng, Ying Yang, Rong Liu, Jian-Zhi Wang, Xiji Shu, Xiaochuan Wang

  Keywords: post-traumatic stress disorder (PTSD), single prolonged stress (SPS), Alzheimer disease (AD), tau phosphorylation, GSK-3β

  Published in Aging on September 23, 2019

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• Research PaperVolume 9, Issue 5pp 1386-1403

  Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer’s disease

  Relevance score: 0.00

  Cyril Bories, Dany Arsenault, Myriam Lemire, Cyntia Tremblay, Yves De Koninck, Frédéric Calon

  Keywords: Alzheimer, p21-activated kinase, frontal cortex, 3xTg-AD mice, electrophysiology, morphology

  Published in Aging on May 16, 2017

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