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Press Release Archive

Page 9 of 25 · 497 total

Leukocyte Telomere Length and Disease Severity in Cystic Fibrosis

09-11-2024

“We hypothesized that CF patients with more severe disease characteristics exhibit shorter leukocyte telomere length (LTL) and greater LTL attrition.” BUFFALO, NY- September 11, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume…

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2-Bromopalmitate Reduces Senescence in Human Cells: Role of Palmitoylation

09-10-2024

“For the first time, the present study revealed a critical role for protein palmitoylation in the development of a DNA damage-induced senescence phenotype.” BUFFALO, NY- September 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science),…

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Effects and Consequences of Cardiac Metabolism in the Elderly

09-04-2024

“We aim to explore the relationship between cardiac metabolism dysfunction and heart failure, emphasizing the need of innovative treatments to manage these interconnected cardiovascular conditions.” BUFFALO, NY- September 4, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)"…

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Proteomic and Secretomic Analysis Reveals Cytoskeleton's Role in Aging

09-03-2024

“Our present data reinforce knowledge about an age-related alteration in the synthesis of major proteins linked to the migratory and contractile functions of dermal human fibroblasts.” BUFFALO, NY- September 3 , 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany…

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Trioxidized Cysteine and Aging: Beyond Proteinopathic Paradigms

08-27-2024

“The results indicated a significant increase in cumulative t-Cys levels and the total number of t-Cys residues in aging and aged mice proteomes compared to young groups.” Listen to an audio version of this press release BUFFALO, NY- August 27, 2024 – A new research perspective was published in Aging (listed by…

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Impact of Exercise on Aging: Highlighting Muscle Biomarkers

08-21-2024

“Here, we presented the first quantitative and qualitative study on the effect of exercise on age-related biomarkers in human skeletal tissues." Listen to an audio version of this press release BUFFALO, NY- August 21, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and…

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How Physical Fitness and Lifestyle Impact Biological Aging

08-20-2024

“Here, we discuss our recent report on the ‘Associations between cardiorespiratory fitness and lifestyle-related factors with DNA methylation-based ageing clocks in older men: WASEDA’S Health Study.’” Listen to an audio version of this press release BUFFALO, NY- August 20, 2024 – A new editorial was published in Aging…

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Cell Death Types and Their Relations to Host Immune Pathways

08-16-2024

“We have proposed a framework encompassing all discovered host immunological pathways, such as TH1, TH2a, TH2b, TH3, TH9, TH17, TH22, TH1-like, and THαβ immune reactions” Listen to an audio version of this press release BUFFALO, NY- August 16, 2024 – A new review was published as the cover paper of Aging (listed by…

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Recalibrating Principles of Epigenetic Aging Clocks in Human Health

08-14-2024

“Our study revealed that the composition of immune cells significantly affects the variation in EAA across six common blood epigenetic clocks." Listen to an audio version of this press release BUFFALO, NY- August 14, 2024 – A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and…

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Lipid Accumulation Drives Cellular Senescence in Dopaminergic Neurons

08-13-2024

"These findings align with our previous results in dopaminergic neurons in highlighting a central role for lipid accumulation in the senescence of DA neurons." Listen to an audio version of this press release BUFFALO, NY- August 13, 2024 – A new research perspective was published in Aging (listed by MEDLINE/PubMed as…

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mTORC1 in Classical Monocytes: Links to Human Size Variation & Neuropsychiatric Disease

08-07-2024

"This report suggests that a simple assay may allow cost-effective prediction of medication response." Listen to an audio version of this press release BUFFALO, NY- August 7, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume…

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Targeted Cancer Therapy: Initial High Concentration May Slow Down Selection for Resistance

08-06-2024

“Unfortunately, any targeted therapy is, always, started with low levels of the drug in the organism, selecting for drug resistance.” Listen to an audio version of this press release BUFFALO, NY- August 6 , 2024 – On July 28, 2024, Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center…

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Association Between Osteoporosis and Telomere Shortening

08-05-2024

“We sought to identify an association between osteoporosis and LTL shortening in an independent prospective cohort.” Listen to an audio version of this press release BUFFALO, NY- August 5 , 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US"…

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Co-analysis of Methylation Platforms for Signatures of Biological Aging in the Domestic Dog

07-23-2024

“In this study, we explore the potential of the three largest, publicly available DNA methylation datasets in dogs to identify signals of biological age.” Listen to an audio version of this press release BUFFALO, NY- July 23 , 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging…

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Modulating Lung Fibroblast Activation via Senolysis of Senescent Human Alveolar Epithelial Cells

07-17-2024

“Novel senomorphic and senolytic agents can be evaluated in this model as they are identified.” Listen to an audio recording of this press release BUFFALO, NY- July 17 , 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16,…

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Roles of PEDF in Exercise-induced Suppression of Senescence and its Impact on Lung Pathology in Mice

07-15-2024

“[...] the present results strongly suggest the potential of PEDF as a myokine linking exercise training to the suppression of senescence.” Listen to an audio version of this press release BUFFALO, NY- July 15 , 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany…

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Aging Exacerbates Oxidative Stress and Liver Fibrosis in Animal Model of Down Syndrome

07-10-2024

“[...] our results put the basis for the use of antioxidants supplementation in Down Syndrome patients to prevent liver-associated pathologies.” Listen to an audio version of this press release BUFFALO, NY- July 10 , 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)"…

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Omics-based Insights Into Vision Decline

07-09-2024

“These findings potentially support employing anti-aging therapies such as senolytic pharmacologic compounds to prevent or ameliorate progression to AMD [...]” Listen to an audio version of this press release BUFFALO, NY- July 9 , 2024 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging…

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A New Concept Towards an Immune Response Against Cancer and Aging: Senescent Cell-derived Vaccines?

07-01-2024

“[...] cancer immunotherapy based on tumor-associated senescent cells and other types of senescent cells may achieve exciting outcomes beyond cancer therapy.” Listen to an audio version of this press release BUFFALO, NY- July 1 , 2024 – A new review paper was published on the cover of Aging (listed by MEDLINE/PubMed…

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Editorial: Global Consensus for Sarcopenia

06-26-2024

“[...] the development of a global conceptual definition of sarcopenia signifies a new dawn for this muscle disease.” Listen to an audio version of this press release BUFFALO, NY- June 26 , 2024 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of…

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