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10-27-2025
“These findings uncover a previously unknown role of TRF1 in regulating metabolism.” Click here to listen to the press release BUFFALO, NY — October 27, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “ Depletion of the TRF1 telomere-binding protein leads to…
10-23-2025
“These results indicate that PAI-1 is partly involved in aging-related sarcopenia and osteopenia in female mice, although the corresponding mechanisms remain unknown.” Click here to listen to the press release BUFFALO, NY — October 23, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on…
10-21-2025
“The major issue is that longevity clinics not yet embedded within mainstream medical practice.” Click here to listen to the press release BUFFALO, NY — October 21, 2025 — A new editorial was published in Aging-US on October 13, 2025, titled “ Longevity clinics: between promise and peril .” In this editorial, Marco…
10-17-2025
“Taken together, these findings reveal a novel role of Runx1 in maintaining disc health and regulating age-related degenerative processes.” Click here to listen to the press release BUFFALO, NY — October 17, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, “…
10-14-2025
“Collectively, these findings suggest that glycocalyx integrity is a critical determinant of physical function and that glycocalyx-targeted interventions may be a viable therapeutic strategy to treat age-related physical dysfunction.” Click here to listen to the press release BUFFALO, NY — October 14, 2025 — A new…
10-09-2025
“This study was designed to investigate the effect of long-term social housing on cognitive decline and neuron ensemble activity dynamics in old age.” Click here to listen to the press release BUFFALO, NY — October 9, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on August 22, 2025,…
10-07-2025
“The findings highlight miRNA-145-5p and miRNA-27b-3p as potential therapeutic targets to address adipose tissue defects and premature aging in HGPS.” Click here to listen to the press release BUFFALO, NY — October 7, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on August 27, 2025,…
10-03-2025
“We recommend that investigators carefully consider what aspects of frailty to include in their analyses instead of fully adopting the published scoring systems.” Click here to listen to the press release BUFFALO, NY — October 3, 2025 — A new research perspective was published in Volume 17, Issue 9 of Aging-US on…
10-01-2025
“These findings establish the significant health-span extension capacity of OT+A5i and emphasize the differences in aging and in response to longevity therapeutics between the sexes.” Click here to listen to the press release BUFFALO, NY — October 1, 2025 — A new research paper featured as the cover of Volume 17,…
09-24-2025
“What emerges is a complex picture that remains insufficient to affirm or negate the longevity and healthspan extending benefits attributed to rapamycin.” Click here to listen to the press release BUFFALO, NY — September 24, 2025 — A new research paper was published in Volume 17, Issue 8 of Aging-US on August 7, 2025,…
09-23-2025
“This data provides the first evidence of selective cell response to senolytic treatment among senescent cell subpopulations.” Click here to listen to the press release BUFFALO, NY — September 23, 2025 — A new research paper was published in Volume 17, Issue 8 of Aging-US on August 7, 2025, titled “ Senescent cell…
09-18-2025
“[...]we have identified FGF21 as a novel biomarker in ALS that is detected in multiple compartments including muscle, spinal cord, and circulation.” Click here to listen to the press release BUFFALO, NY — September 18, 2025 — A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025,…
09-16-2025
“We believe that our findings will incentivize further studies to identify the best disease-modifying therapy for early PD without dementia.” Click here to listen to this press release BUFFALO, NY — September 16, 2025 — A new research paper was published in Volume 17, Issue 8 of Aging-US on August 6, 2025, titled “…
09-11-2025
“Our findings establish novel connections between aging biology and IPF pathogenesis while demonstrating the potential of AI-guided approaches in therapeutic development for age-related diseases.” Click here to listen to the press release BUFFALO, NY — September 11, 2025 — A new research paper was published in Volume…
09-09-2025
“These results support the role of gut microbiome as modulator of the inflammatory and cardiometabolic circuits, that may contribute to the onset of age-related diseases [...]” Click here to listen to the press release BUFFALO, NY — September 9, 2025 — A new research paper was published in Volume 17, Issue 8 of…
09-04-2025
“In this review, we propose hallmark decomposition as a method of measuring the potential of a therapy to translate from a disease-specific treatment to a general geroprotector.” Click here to listen to the press release BUFFALO, NY — September 4, 2025 — A new research perspective was published in Volume 17, Issue 8…
09-02-2025
“This can help understand the global molecular mechanisms underlying aging and age-related diseases and potentially identify novel therapeutic targets or biomarkers to target and regulate senescent cell-secreted exosomes or use them as therapeutic agents.” Click here to listen to the press release BUFFALO, NY —…
08-27-2025
“Thus, our studies revealed regulatory mechanisms of glycolysis-driven cellular senescence by AUF1-mediated decay of PGAM1 and PDP2 mRNAs.” Click here to listen to the press release BUFFALO, NY — August 27, 2025 — A new research paper was published in Volume 17, Issue 7 of Aging ( Aging-US ) on July 24, 2025, titled “…
08-26-2025
“These findings highlight the potential role of DNAm in cognitive function.” Click here to listen to the press release BUFFALO, NY — August 26, 2025 — A new research paper was published in Volume 17, Issue 7 of Aging ( Aging-US ) on July 21, 2025, titled “ Association of DNA methylation age acceleration with digital…
08-21-2025
“[...]age estimation on blood stains from cancer patients might not result in significantly higher estimation errors, except for very aggressive forms of cancer.” Click here to listen to the press release BUFFALO, NY — August 21, 2025 — A new research paper was published in Volume 17, Issue 7 of Aging ( Aging-US ) on…