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Press Release Archive

Page 17 of 25 · 497 total

Isoform-Specific AMPK Repression Affects Cognitive Function in Aged Mice

03-07-2023

“The study indicates that the aging process might have distinct impact on the signaling pathways associated with the AMPKα isoforms [...]” Listen to an audio version of this press release BUFFALO, NY- March 7, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a…

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Cellular Senescence: When Growth Stimulation Meets Cell Cycle Arrest

03-02-2023

“Growth and aging are driven by overlapping signaling pathways.” Listen to an audio version of this press release BUFFALO, NY- March 2, 2023 – Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) published a new review paper in Volume 15, Issue 4 , entitled, “ Cellular senescence:…

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Telomere Shortening Linked to Depression and Cognitive Impairment in Older Adults

02-28-2023

“[...] we believe that our findings will help prevent and treat depression and cognitive impairment in the healthy elderly.” Listen to an audio version of this press release BUFFALO, NY- February 28, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and…

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Metformin's Impact on Aging and Longevity Through DNA Methylation

02-22-2023

“In this study, we compared genome-wide DNA methylation rates among metformin users and nonusers [...]” Listen to an audio version of this press release BUFFALO, NY- February 22, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume…

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Epigenetic Age and Lung Cancer Risk in the CLUE II Prospective Cohort Study

02-16-2023

“In this nested case-control study on incident lung cancer, we observed no positive associations between lung cancer risk and epigenetic age acceleration [...]” Listen to an audio version of this press release BUFFALO, NY- February 16, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)"…

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Immune-Mediated Platelet Depletion Augments Alzheimer’s Disease in Mice

02-15-2023

“Our study suggests that platelets might contribute to limiting amyloid plaque size and neuronal damage, having a beneficial role in AD [Alzheimer’s disease].” Listen to an audio version of this press release BUFFALO, NY- February 15, 2023 – A new research paper was published on the cover of Aging (listed as "Aging…

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Body Weight Influences Musculoskeletal Adaptation to Running in Aging Mice

02-08-2023

“[...] [voluntary wheel running] differentially alters bone parameters depending on body weight [...]” Listen to an audio version of this press release BUFFALO, NY- February 8, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume…

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Are Menopause, Aging and Prostate Cancer Diseases?

02-02-2023

“Aging can be understood through the development of all quasi-programmed diseases.” Listen to an audio version of this press release BUFFALO, NY- February 2, 2023 – A new research perspective was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2 ,…

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Clearance of p16Ink4a+ Cells: Limited Effects on β-Cell Mass and Proliferation in Mice

01-31-2023

“[...] we set out to explore the effects of removing p16Ink4a+ senescent cells on the proliferative capacity and mass of β-cells [...].” Listen to an audio version of this press release BUFFALO, NY- January 31, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by…

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The Innate Immune Signaling Component FBXC-58 Mediates Dietary Restriction Effects on Healthy Aging in Caenorhabditis elegans

01-25-2023

“In this study, we found that DR prevents muscle aging via fbxc-58 in C. elegans.” Listen to an audio version of this press release BUFFALO, NY- January 25, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1 ,…

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Genetic Deficiency and Pharmacological Modulation of RORα Regulate Laser-Induced Choroidal Neovascularization

01-18-2023

“In this study, we present findings for a protective role of RORα in a mouse laser-induced CNV model of neovascular AMD.” Listen to an audio version of this press release BUFFALO, NY- January 18, 2023 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web…

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Single-Cell Transcriptomics of Peripheral Blood in the Aging Mouse

01-16-2023

“Here, we profiled 14588 single cells from the mouse blood and assessed the differences between young and old mice.” Listen to an audio version of this press release BUFFALO, NY- January 16, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US"…

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Transcriptomic Analysis of Human ALS Skeletal Muscle Reveals Disease-Specific Pattern of Dysregulated circRNAs

01-12-2023

“In this work, we have identified distinct patterns of circRNA expression in human ALS muscle tissue, many appearing to be disease-specific, that display expression gradients at different levels within the CNS.” Listen to an audio version of this press release BUFFALO, NY- January 12, 2023 – A new research paper was…

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Epigenetic Aging Associated With Aberrant Neural Oscillatory Dynamics Serving Visuospatial Processing in People With HIV

01-05-2023

“Thus, these findings are the first to identify the interaction between biological age and HIV status on neural oscillatory dynamics serving cognitive function, and more specifically, visuospatial processing.” Listen to an audio version of this press release BUFFALO, NY- January 5, 2023 – A new research paper was…

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Associations of APOE ε2 and ε4 Alleles and Polygenic Profiles Comprising APOE-TOMM40-APOC1 Variants With Alzheimer’s Disease Biomarkers

01-03-2023

“The thickness of the arrows denotes tighter (thick lines) and weaker (thin lines) links between genetic variants, AD biomarkers, and cognitive impairment.” Listen to an audio version of this press release BUFFALO, NY- January 3, 2023 – A new research paper was published on the cover of Aging (listed as "Aging (Albany…

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Aging | DNA Methylation-Based Measures of Biological Aging and Cognitive Decline Over 16-years: Preliminary Longitudinal Findings in Midlife

12-29-2022

“This is the first report to explore changes over time in several of the latest DNAm biological aging measures [...]” Listen to an audio version of this press release BUFFALO, NY- December 29, 2022 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of…

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Aging | White Matter Hyperintensity Load Associated With Premature Brain Aging

12-22-2022

“Our results support previous work suggesting there is a relationship between chronological age and WMH [white matter hyperintensities] volume, and chronological age and estimated brain age.” Listen to an audio version of this press release BUFFALO, NY- December 22, 2022 – A new research paper was published in Aging…

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Aging | DNA Methylation GrimAge Version 2

12-21-2022

“[...] GrimAge2 complements existing clinical biomarkers when evaluating an individual’s aging rate.” Listen to an audio version of this press release BUFFALO, NY- December 21, 2022 – A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume…

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Aging | Single Nuclei Profiling Identifies Cell Specific Markers of Skeletal Muscle Aging, Frailty, and Senescence

12-15-2022

“Our study provides several insights into human skeletal muscle aging.” BUFFALO, NY- December 15, 2022 – A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23 , entitled, “ Single nuclei profiling identifies cell…

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Aging | Organotypic Cultures as Aging Associated Disease Models

12-14-2022

“[...] many aging researchers may be unaware of recent progress in organotypic models [...]” BUFFALO, NY- December 14, 2022 – A new review was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 22 , entitled, “ Organotypic cultures as aging associated…

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