Volume 4, Issue 7

July 2012pp 448—520

Editorial Comment

Why is DNA methylation of Igf2 CpG island shore affected during ageing?

Paola Caiafa, Michele Zampieri

https://doi.org/10.18632/aging.100473pp 448—449

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Research Perspective

Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?

Mikhail V. Blagosklonny

https://doi.org/10.18632/aging.100475pp 450—455

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Research Papers

An autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cells

Patricia S. Pardo, Aladin M. Boriek

https://doi.org/10.18632/aging.100470pp 456—461

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Methylation by Set9 modulates FoxO3 stability and transcriptional activity

Daniel R. Calnan, Ashley E. Webb, Jamie L. White, Timothy R. Stowe, Tapasree Goswami, Xiaobing Shi, Alexsandra Espejo, Mark T. Bedford, Or Gozani, Steven P. Gygi, Anne Brunet

https://doi.org/10.18632/aging.100471pp 462—479

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Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs

Bruna Corominas-Faja, Rosa Quirantes-Piné, Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Sílvia Cufí, Begoña Martin-Castillo, Vicente Micol, Jorge Joven, Antonio Segura-Carretero, Javier A. Menendez

https://doi.org/10.18632/aging.100472pp 480—498

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The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction

Brenda Rascón, Basil P. Hubbard, David A. Sinclair, Gro V. Amdam

pp 499—508

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Space/Population and Time/Age in DNA methylation variability in humans: a study on IGF2/H19 locus in different Italian populations and in mono- and di-zygotic twins of different age

Chiara Pirazzini, Cristina Giuliani, Maria Giulia Bacalini, Alessio Boattini, Miriam Capri, Elisa Fontanesi, Elena Marasco, Vilma Mantovani, Michela Pierini, Elisa Pini, Donata Luiselli, Claudio Franceschi, Paolo Garagnani

https://doi.org/10.18632/aging.100476pp 509—520

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