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• Research PaperVolume 16, Issue 9pp 7704-7732

  Immune cell senescence and exhaustion promote the occurrence of liver metastasis in colorectal cancer by regulating epithelial-mesenchymal transition

  Relevance score: 0.00

  Sen Lin, Lanyue Ma, Jiaxin Mo, Ruiqi Zhao, Jinghao Li, Mengjiao Yu, Mei Jiang, Lisheng Peng

  Keywords: senescence, exhaustion, colorectal cancer liver metastases, epithelium-mesenchymal transition, machine learning

  Published in Aging on April 26, 2024

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• Research PaperVolume 8, Issue 10pp 2337-2354

  TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response

  Relevance score: 0.00

  Zhi-Yuan Li, Zhao-Li Chen, Ting Zhang, Chao Wei, Wei-Yun Shi

  Keywords: corneal epithelium, cellular senescence, transforming growth factor-β, RNA stress granules, nuclear factor-κB

  Published in Aging on October 6, 2016

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• Research PaperVolume 13, Issue 8pp 11010-11025

  Obacunone protects retinal pigment epithelium cells from ultra-violet radiation-induced oxidative injury

  Relevance score: 0.00

  Da-Rui Huang, Chang-Ming Dai, Shu-Yan Li, Xiao-Feng Li

  Keywords: obacunone, UV radiation, retinal pigment epithelium cells, Nrf2 signaling, oxidative injury

  Published in Aging on February 1, 2021

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• Research PaperVolume 12, Issue 14pp 13905-13923

  Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

  Relevance score: 0.00

  Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins

  Keywords: age-related macular degeneration, retinal pigment epithelium, inflammation, C-reactive protein

  Published in Aging on July 16, 2020

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• Research PaperVolume 10, Issue 6pp 1306-1323

  Loss of NAMPT in aging retinal pigment epithelium reduces NAD⁺ availability and promotes cellular senescence

  Relevance score: 0.00

  Ravirajsinh N. Jadeja, Folami L. Powell, Malita A. Jones, Jasmine Fuller, Ethan Joseph, Menaka C. Thounaojam, Manuela Bartoli, Pamela M. Martin

  Keywords: retinal pigment epithelium (RPE), aging, age-related macular degeneration (AMD), NAD+, NAMPT, senescence, SIRT1

  Published in Aging on June 12, 2018

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• Research PaperVolume 3, Issue 1pp 44-54

  Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats

  Relevance score: 0.00

  Anton M. Markovets, Valeriya B. Saprunova, Anna A. Zhdankina, Anzhella Zh. Fursova, Lora E. Bakeeva, Natalia G. Kolosova

  Keywords: age-related macular degeneration, OXYS rats, molecular mechanism of pathogenesis, vascular endothelial growth factor, pigment epithelium-derived factor

  Published in Aging on December 12, 2010

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• Research PaperVolume 17, Issue 3pp 657-684

  Deciphering age-related transcriptomic changes in the mouse retinal pigment epithelium

  Relevance score: 0.00

  Sushil K. Dubey, Rashmi Dubey, Kyungsik Jung, Alvaro G. Hernandez, Mark E. Kleinman

  Keywords: transcriptome, retinal pigment epithelium, oxidative stress, inflammation, chronological aging

  Published in Aging on March 4, 2025

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• Research PaperVolume 9, Issue 10pp 2052-2068

  PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation

  Relevance score: 0.00

  Dinusha Rajapakse, Mei Chen, Tim M. Curtis, Heping Xu

  Keywords: aging, multinucleation, retinal pigment epithelium, protein kinase C, p27kip1

  Published in Aging on October 9, 2017

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• Research PaperVolume 13, Issue 18pp 22040-22058

  A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin

  Relevance score: 0.00

  Valérie Fontaine, Mylène Fournié, Elodie Monteiro, Thinhinane Boumedine, Christine Balducci, Louis Guibout, Mathilde Latil, José-Alain Sahel, Stanislas Veillet, Pierre J. Dilda, René Lafont, Serge Camelo

  Keywords: N-retinylidene-N-retinylethanolamine (A2E), norbixin, peroxisome proliferator-activated receptor (PPAR), retinal pigment epithelium (RPE), retinoic X receptor (RXR)

  Published in Aging on September 20, 2021

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 13, Issue 5pp 7589-7607

  Fecal microbiota transplantation mitigates vaginal atrophy in ovariectomized mice

  Relevance score: 0.00

  Jia Huang, Wanying Shan, Fuxia Li, Zizhuo Wang, Jing Cheng, Funian Lu, Ensong Guo, Rajluxmee Beejadhursing, Rourou Xiao, Chen Liu, Bin Yang, Xi Li, Yu Fu, Ling Xi, Shixuan Wang, Ding Ma, Gang Chen, Chaoyang Sun

  Keywords: genitourinary syndrome of menopause, vulvovaginal atrophy, ovariectomized mouse model, vaginal epithelium, gut microbiota

  Published in Aging on February 26, 2021

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• CommentaryVolume 2, Issue 1pp 3-6

  Stem cells in aged mammalian ovaries

  Relevance score: 0.00

  Irma Virant-Klun, Thomas Skutella

  Keywords: aging, cancer, ovary, ovarian surface epithelium, stem cells

  Published in Aging on January 26, 2010