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• Research PaperVolume 12, Issue 18pp 18127-18136

  GHR knockdown enhances the sensitivity of HCC cells to sorafenib

  Relevance score: 0.00

  Shuang Gao, Qianwen Ni, Xiuli Wu, Tieliu Cao

  Keywords: hepatocellular carcinoma, sorafenib, GHR, resistance, PI3K/AKT/ERK1/2 signaling pathway

  Published in Aging on September 24, 2020

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• Research PaperVolume 12, Issue 18pp 18033-18051

  Insulin sensitivity in long-lived growth hormone-releasing hormone knockout mice

  Relevance score: 0.00

  Fang Zhang, Mert Icyuz, Zhenghui Liu, Michael Fitch, Liou Y. Sun

  Keywords: GHRH^-/- mice, tissues-specific insulin signaling, hyperinsulinemic-euglycemic clamp, AKT/S6, ERK1/2

  Published in Aging on July 8, 2020

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• Research PaperVolume 12, Issue 10pp 9761-9780

  Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone

  Relevance score: 0.00

  Mert Icyuz, Michael Fitch, Fang Zhang, Anil Challa, Liou Y. Sun

  Keywords: GHRH, metabolism, aging, lifespan, CRISPR

  Published in Aging on May 18, 2020

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• Research PaperVolume 8, Issue 1pp 178-191

  Ghrelin receptor regulates adipose tissue inflammation in aging

  Relevance score: 0.00

  Ligen Lin, Jong Han Lee, Eric D. Buras, Kaijiang Yu, Ruitao Wang, C. Wayne Smith, Huaizhu Wu, David Sheikh-Hamad, Yuxiang Sun

  Keywords: ghrelin, growth hormone secretagogue receptor (GHS-R), adipose tissue macrophages (ATMs), inflammation, peritoneal macrophages (PM), thermogenesis

  Published in Aging on January 30, 2016

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• Research PaperVolume 6, Issue 12pp 1019-1032

  The suppression of ghrelin signaling mitigates age-associated thermogenic impairment

  Relevance score: 0.00

  Ligen Lin, Jong Han Lee, Odelia Y. N. Bongmba, Xiaojun Ma, Xiongwei Zhu, David Sheikh-Hamad, Yuxiang Sun

  Keywords: ghrelin, growth hormone secretagogue receptor (GHSR), brown adipose tissue (BAT), thermogenesis, insulin signaling, mitochondrial biogenesis and dynamics

  Published in Aging on December 15, 2014

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• Research PaperVolume 3, Issue 11pp 1092-1097

  Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus

  Relevance score: 0.00

  Yuko Maejima, Daisuke Kohno, Yusaku Iwasaki, Toshihiko Yada

  Keywords: ghrelin, insulin, neuropeptide Y, arcuate nucleus, insulin receptor, cytosolic Ca2+, hypothalamus

  Published in Aging on November 8, 2011

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• Research PaperVolume 7, Issue 9pp 616-628

  Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease

  Relevance score: 0.00

  Alexey Moskalev, Elizaveta Chernyagina, João Pedro de Magalhães, Diogo Barardo, Harikrishnan Thoppil, Mikhail Shaposhnikov, Arie Budovsky, Vadim E. Fraifeld, Andrew Garazha, Vasily Tsvetkov, Evgeny Bronovitsky, Vladislav Bogomolov, Alexei Scerbacov, Oleg Kuryan, Roman Gurinovich, Leslie C. Jellen, Brian Kennedy, Polina Mamoshina, Evgeniya Dobrovolskaya, Alex Aliper, Dmitry Kaminsky, Alex Zhavoronkov

  Keywords: growth hormone receptor (GHR), muscle-specific knockout, lifespan, aging, frailty, pathology, body composition

  Published in Aging on September 2, 2015

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• Research PaperVolume 7, Issue 7pp 500-512

  Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR−/− mice

  Relevance score: 0.00

  Edward O. List, Darlene E. Berryman, Yuji Ikeno, Gene B. Hubbard, Kevin Funk, Ross Comisford, Jonathan A. Young, Michael B. Stout, Tamar Tchkonia, Michal M. Masternak, Andrzej Bartke, James L. Kirkland, Richard A. Miller, John J. Kopchick

  Keywords: growth hormone receptor (GHR), muscle-specific knockout, lifespan, aging, frailty, pathology, body composition

  Published in Aging on June 29, 2015

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• Research PaperVolume 4, Issue 11pp 755-767

  Beneficial effects of novel antagonists of GHRH in different models of Alzheimer's disease

  Relevance score: 0.00

  Miklos Jaszberenyi, Ferenc G. Rick, Luca Szalontay, Norman L. Block, Marta Zarandi, Ren-Zhi Cai, Andrew V. Schally

  Keywords: Alzheimer's disease, growth hormone-releasing hormone, GHRH, 5XFAD mice, transgenic model, HCN-2 cell line, Morris water maze

  Published in Aging on November 29, 2012

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• Research PaperVolume 17, Issue 2pp 393-407

  Exploring the role of acylated ghrelin and gut microbiome in delineating cognitive health in the elderly

  Relevance score: 0.00

  Sudeshna Rout, Rishikesh Dash, Varsha Satish, Giriprasad Venugopal, Bodepudi Narasimha Rao, Debapriya Bandhyopadhyay, Sanjeev Kumar Bhoi, Balamurugan Ramadass

  Keywords: gut microbiome, gut-brain axis, ghrelin, AG/UAG ratio, neural network model, dementia

  Published in Aging on February 7, 2025

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• Research PaperVolume 8, Issue 7pp 1470-1484

  Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

  Relevance score: 0.00

  Marisa Ferreira-Marques, Célia A. Aveleira, Sara Carmo-Silva, Mariana Botelho, Luís Pereira de Almeida, Cláudia Cavadas

  Keywords: neuropeptide Y (NPY), ghrelin, caloric restriction, autophagy, cortical neurons

  Published in Aging on July 20, 2016

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• EditorialVolume 10, Issue 8pp 1795-1796

  Correction of aging phenotype in the liver

  Relevance score: 0.00

  Katherine Rodriguez, Ashley Cast, Nikolai A. Timchenko

  Keywords: aging, steatosis, epigenetic, ghrelin, C/EBPa, cdk4

  Published in Aging on August 10, 2018