Volume 11, Issue 9

May 15, 2019pp 2542—2911

About the Cover

The cover features Figure 8 "Overall contribution of age to BPH pathogenic mechanisms. BPH/LUTD is a disease that occurs through the normal course of aging and often manifests clinically as bladder outlet obstruction (BOO)." from Liu et al.

Editorials

Aging and ischemic stroke

Mohammed Yousufuddin, Nathan Young

https://doi.org/10.18632/aging.101931pp 2542—2544

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Physical activity, CVD, and older adults

Richard A. Ferraro, Vincent A. Pallazola, Erin D. Michos

https://doi.org/10.18632/aging.101942pp 2545—2546

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MicroRNA Let-7 in B lymphocyte activation

Shuai Jiang, Wei Yan, Shizhen Emily Wang

https://doi.org/10.18632/aging.101968pp 2547—2548

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Acute coronary syndrome and postprandial delayed hyperchylomicronemia

Fumitaka Okajima, Osamu Kurihara, Masamichi Takano

https://doi.org/10.18632/aging.101969pp 2549—2550

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Research Papers

MiR-124 sensitizes cisplatin-induced cytotoxicity against CD133⁺ hepatocellular carcinoma cells by targeting SIRT1/ROS/JNK pathway

Yunxiuxiu Xu, Yu Lai, Hanqin Weng, Lanping Tan, Yanshan Li, Guangcheng Chen, Xingxi Luo, Yibiao Ye

https://doi.org/10.18632/aging.101876pp 2551—2564

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Modulation of Coenzyme Q₁₀ content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging

Fabio Marcheggiani, Ilenia Cirilli, Patrick Orlando, Sonia Silvestri, Alexandra Vogelsang, Anja Knott, Thomas Blatt, Julia M. Weise, Luca Tiano

https://doi.org/10.18632/aging.101926pp 2565—2582

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Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice

Zhaomeng Sun, Lijun Zhao, Li Su, Qing Fang, Chenzhong Xu, Yuanyuan Su, Yao Liang, Guodong Li, Yanxue Xue, Tanjun Tong, Jun Chen

https://doi.org/10.18632/aging.101932pp 2583—2609

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A novel mRNA-miRNA-lncRNA competing endogenous RNA triple sub-network associated with prognosis of pancreatic cancer

Wenlong Wang, Weiyang Lou, Bisha Ding, Beng Yang, Hongda Lu, Qingzhi Kong, Weimin Fan

https://doi.org/10.18632/aging.101933pp 2610—2627

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Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer

Weiyang Lou, Jingxing Liu, Bisha Ding, Luqi Jin, Liang Xu, Xia Li, Jing Chen, Weimin Fan

https://doi.org/10.18632/aging.101934pp 2628—2652

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Prostate enlargement and altered urinary function are part of the aging process

Teresa T. Liu, Samuel Thomas, Dalton T. Mclean, Alejandro Roldan-Alzate, Diego Hernando, Emily A. Ricke, William A. Ricke

https://doi.org/10.18632/aging.101938pp 2653—2669

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Downregulation of miR-125b promotes resistance of glioma cells to TRAIL through overexpression of Tafazzin which is a mitochondrial protein

Wenjia Ma, Yan Cui, Min Liu, Zhigang Tan, Yugang Jiang

https://doi.org/10.18632/aging.101939pp 2670—2680

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Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis

Jing Xie, Chien-shan Cheng, Xiao Yan Zhu, Ye Hua Shen, Li Bin Song, Hao Chen, Zhen Chen, Lu Ming Liu, Zhi Qiang Meng

https://doi.org/10.18632/aging.101940pp 2681—2698

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Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract

Yu Yan, Haiyang Yu, Liyao Sun, Hanruo Liu, Chao Wang, Xi Wei, Fanqian Song, Hulun Li, Hongyan Ge, Hua Qian, Xiaoguang Li, Xianling Tang, Ping Liu

https://doi.org/10.18632/aging.101943pp 2699—2723

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Rosiglitazone has a neutral effect on the risk of dementia in type 2 diabetes patients

Chin-Hsiao Tseng

https://doi.org/10.18632/aging.101944pp 2724—2734

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RON and RONΔ160 promote gastric cancer cell proliferation, migration, and adaption to hypoxia via interaction with β-catenin

Donghui Zhou, Ling Huang, Yong Zhou, Tao Wei, Lina Yang, Chao Li

https://doi.org/10.18632/aging.101945pp 2735—2748

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Male age: negative impact on sperm DNA fragmentation

Elena Albani, Stefano Castellano, Bruna Gurrieri, Luisa Arruzzolo, Luciano Negri, Elena M. Borroni, Paolo E. Levi-Setti

https://doi.org/10.18632/aging.101946pp 2749—2761

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MiR-191 inhibit angiogenesis after acute ischemic stroke targeting VEZF1

Kang Du, Can Zhao, Li Wang, Yue Wang, Kang-Zhen Zhang, Xi-Yu Shen, Hui-Xian Sun, Wei Gao, Xiang Lu

https://doi.org/10.18632/aging.101948pp 2762—2786

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The role of ORMDL3/ATF6 in compensated beta cell proliferation during early diabetes

Weixia Yang, Feifei Sheng, Baolan Sun, Shane Fischbach, Xiangwei Xiao

https://doi.org/10.18632/aging.101949pp 2787—2796

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Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in chondrocytes

Li Yan, Li Zhou, Danting Xie, Wenxi Du, Fangming Chen, Qiang Yuan, Peijian Tong, Letian Shan, Thomas Efferth

https://doi.org/10.18632/aging.101952pp 2797—2811

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LINC00857 knockdown inhibits cell proliferation and induces apoptosis via involving STAT3 and MET oncogenic proteins in esophageal adenocarcinoma

Wenmei Su, Lihui Wang, Feiyu Niu, Lei Zou, Chunfang Guo, Zhuwen Wang, Xiao Yang, Jiancong Wu, Yi Lu, Jian Zhang, David G. Beer, Zhixiong Yang, Guoan Chen

https://doi.org/10.18632/aging.101953pp 2812—2821

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Phloretin protects against cardiac damage and remodeling via restoring SIRT1 and anti-inflammatory effects in the streptozotocin-induced diabetic mouse model

Yin Ying, Cheng Jiang, Meiling Zhang, Jiye Jin, Shuyu Ge, Xiaodong Wang

https://doi.org/10.18632/aging.101954pp 2822—2835

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Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia

Hetao Song, Zhicai Zuo, Zhuangzhi Yang, Caixia Gao, Kejie Chen, Jing Fang, Hengmin Cui, Ping Ouyang, Junliang Deng, Yi Geng, Hongrui Guo

https://doi.org/10.18632/aging.101956pp 2836—2851

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Poly(ADP-ribosyl)ation and DNA repair synthesis in the extracts of naked mole rat, mouse, and human cells

Anastasiya A. Kosova, Mikhail M. Kutuzov, Alexei N. Evdokimov, Ekaterina S. Ilina, Ekaterina A. Belousova, Svetlana A. Romanenko, Vladimir A. Trifonov, Svetlana N. Khodyreva, Olga I. Lavrik

https://doi.org/10.18632/aging.101959pp 2852—2873

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Metformin induces a fasting- and antifolate-mimicking modification of systemic host metabolism in breast cancer patients

Elisabet Cuyàs, Salvador Fernández-Arroyo, Maria Buxó, Sonia Pernas, Joan Dorca, Isabel Álvarez, Susana Martínez, Jose Manuel Pérez-Garcia, Norberto Batista-López, César A. Rodríguez-Sánchez, Kepa Amillano, Severina Domínguez, Maria Luque, Idoia Morilla, Agostina Stradella, Gemma Viñas, Javier Cortés, Sara Verdura, Joan Brunet, Eugeni López-Bonet, Margarita Garcia, Samiha Saidani, Jorge Joven, Begoña Martin-Castillo, Javier A. Menendez

https://doi.org/10.18632/aging.101960pp 2874—2888

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c-Met as a new marker of cellular senescence

Maria Boichuck, Jonathan Zorea, Moshe Elkabets, Marina Wolfson, Vadim E. Fraifeld

https://doi.org/10.18632/aging.101961pp 2889—2897

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miR-495 inhibits the growth of fibroblasts in hypertrophic scars

Bingyu Guo, Qiang Hui, Zhishan Xu, Peng Chang, Kai Tao

https://doi.org/10.18632/aging.101965pp 2898—2910

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Correction

Correction for: Accelerated DNA methylation age and the use of antihypertensive medication among older adults

Xu Gao, Elena Colicino, Jincheng Shen, Allan C. Just, Jamaji C. Nwanaji-Enwerem, Brent Coull, Xihong Lin, Pantel Vokonas, Yinan Zheng, Lifang Hou, Joel Schwartz, Andrea A. Baccarelli

https://doi.org/10.18632/aging.101980pp 2911

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