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Special Collection on Eye Disease

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miR-106b suppresses pathological retinal angiogenesis

Catherine Ménard, Ariel M. Wilson, Agnieszka Dejda, Khalil Miloudi, François Binet, Sergio Crespo-Garcia, Célia Parinot, Frédérique Pilon, Rachel Juneau, Elisabeth MMA Andriessen, Gaëlle Mawambo, John Paul SanGiovanni, Vincent De Guire, Przemyslaw Sapieha

https://doi.org/10.18632/aging.202404pp 24836—24852

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Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury

Jing-Yao Song, Bin Fan, Lin Che, Yi-Ran Pan, Si-Ming Zhang, Ying Wang, Victoria Bunik, Guang-Yu Li

https://doi.org/10.18632/aging.103846pp 16579—16596

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Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins

https://doi.org/10.18632/aging.103655pp 13905—13923

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Role of Citicoline in an in vitro AMD model

Sonali Nashine, M. Cristina Kenney

https://doi.org/10.18632/aging.103164pp 9031—9040

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Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease

Valérie Fontaine, Elodie Monteiro, Mylène Fournié, Elena Brazhnikova, Thinhinane Boumedine, Cécile Vidal, Christine Balducci, Louis Guibout, Mathilde Latil, Pierre J. Dilda, Stanislas Veillet, José-Alain Sahel, René Lafont, Serge Camelo

https://doi.org/10.18632/aging.103014pp 6151—6171

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PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

https://doi.org/10.18632/aging.102179pp 6691—6713

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HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration

Shuo Sun, Bincui Cai, Yao Li, Wenqi Su, Xuzheng Zhao, Boteng Gong, Zhiqing Li, Xiaomin Zhang, Yalin Wu, Chao Chen, Stephen H. Tsang, Jin Yang, Xiaorong Li

https://doi.org/10.18632/aging.102039pp 4323—4337

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Nutraceutical effects of Emblica officinalis in age-related macular degeneration

Sonali Nashine, Raj Kanodia, Anthony B. Nesburn, Girish Soman, Baruch D. Kuppermann, M. Cristina Kenney

https://doi.org/10.18632/aging.101820pp 1177—1188

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A comprehensive evaluation of 181 reported CHST6 variants in patients with macular corneal dystrophy

Jing Zhang, Dan Wu, Yue Li, Yidan Fan, Yiqin Dai, Jianjiang Xu

https://doi.org/10.18632/aging.101807pp 1019—1029

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Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells

Raffaella Lazzarini, Michele Nicolai, Vittorio Pirani, Cesare Mariotti, Roberto Di Primio

https://doi.org/10.18632/aging.101624pp 3173—3184

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p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model

Nataliya G. Kolosova, Oyuna S. Kozhevnikova, Darya V. Telegina, Anzhela Zh. Fursova, Natalia A. Stefanova, Natalia A. Muraleva, Franco Venanzi, Michael Y. Sherman, Sergey I. Kolesnikov, Albert A. Sufianov, Vladimir L. Gabai, Alexander M. Shneider

https://doi.org/10.18632/aging.101537pp 2136—2147

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Loss of NAMPT in aging retinal pigment epithelium reduces NAD⁺ availability and promotes cellular senescence

Ravirajsinh N. Jadeja, Folami L. Powell, Malita A. Jones, Jasmine Fuller, Ethan Joseph, Menaka C. Thounaojam, Manuela Bartoli, Pamela M. Martin

https://doi.org/10.18632/aging.101469pp 1306—1323

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ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum

Pan Long, Mengshan He, Weiming Yan, Wei Chen, Dongyu Wei, Siwang Wang, Zuoming Zhang, Wei Ge, Tao Chen

https://doi.org/10.18632/aging.202325pp 2750—2767

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Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo

Bojing Yan, Lixin Gao, Yingxiang Huang, Xiaolei Wang, Xuqiang Lang, Fancheng Yan, Bo Meng, Xiaowei Sun, Genlin Li, Yanling Wang

https://doi.org/10.18632/aging.202245

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Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina

Ning Wang, Zhiwen Luo, Ming Jin, Weiwei Sheng, Han-Tsing Wang, Xinyi Long, Yue Wu, Piaopiao Hu, Hong Xu, Xu Zhang

https://doi.org/10.18632/aging.101966pp 3117—3137

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The senescent vision: dysfunction or neuronal loss?

Francisco M. Nadal-Nicolás, Manuel Vidal-Sanz, Marta Agudo-Barriuso

https://doi.org/10.18632/aging.101734pp 15—17

Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice

Yuji Morita, Kenta Jounai, Akihiko Sakamoto, Yasuyuki Tomita, Yoshihiko Sugihara, Hiroaki Suzuki, Konomi Ohshio, Masato Otake, Daisuke Fujiwara, Osamu Kanauchi, Mitsuo Maruyama

https://doi.org/10.18632/aging.101583pp 2723—2740

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The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye

Chang Luo, Jiawu Zhao, Mei Chen, Heping Xu

https://doi.org/10.18632/aging.101474pp 1380—1389

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Age-related changes in eye lens biomechanics, morphology, refractive index and transparency

Catherine Cheng, Justin Parreno, Roberta B. Nowak, Sondip K. Biswas, Kehao Wang, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Juliet A. Moncaster, Woo-Kuen Lo, Barbara Pierscionek, Velia M. Fowler

https://doi.org/10.18632/aging.102584pp 12497—12531

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Pineal gland volume is associated with prevalent and incident isolated rapid eye movement sleep behavior disorder

Jeongbin Park, Ji Won Han, Seung Wan Suh, Seonjeong Byun, Ji Hyun Han, Jong Bin Bae, Jae Hyoung Kim, Ki Woong Kim

https://doi.org/10.18632/aging.102661pp 884—893

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Abnormalities of saccadic eye movements in dementia due to Alzheimer’s disease and mild cognitive impairment

Thomas D.W. Wilcockson, Diako Mardanbegi, Baiqiang Xia, Simon Taylor, Pete Sawyer, Hans W. Gellersen, Ira Leroi, Rebecca Killick, Trevor J. Crawford

https://doi.org/10.18632/aging.102118pp 5389—5398

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Involvement of adiponectin in age-related increases in tear production in mice

Yosuke Shikama, Mie Kurosawa, Masae Furukawa, Naozumi Ishimaru, Kenji Matsushita

https://doi.org/10.18632/aging.102322pp 8329—8346

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ALKBH5-mediated m⁶A demethylation of FOXM1 mRNA promotes progression of uveal melanoma

Lili Hao, Jiayang Yin, Hong Yang, Chaoxuan Li, Linxin Zhu, Lian Liu, Jingxiang Zhong

https://doi.org/10.18632/aging.202371pp 4045—4062

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Development and validation of an immune and stromal prognostic signature in uveal melanoma to guide clinical therapy

Qianwen Gong, Qi Wan, Anqi Li, Yubin Yu, Xiangyu Ding, Lei Lin, Xiaoliang Qi, Liang Hu

https://doi.org/10.18632/aging.103779pp 20254—20267

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Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells

Sebastiano Giallongo, Michelino Di Rosa, Rosario Caltabiano, Lucia Longhitano, Michele Reibaldi, Alfio Distefano, Oriana Lo Re, Angela Maria Amorini, Lidia Puzzo, Lucia Salvatorelli, Stefano Palmucci, Daniele Tibullo, Andrea Russo, Antonio Longo, Giacomo Lazzarino, Giovanni Li Volti, Manlio Vinciguerra

https://doi.org/10.18632/aging.103241pp 9745—9760

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Immunological analyses reveal an immune subtype of uveal melanoma with a poor prognosis

Hui Pan, Linna Lu, Junqi Cui, Yuan Yang, Zhaoyang Wang, Xianqun Fan

https://doi.org/10.18632/aging.102693pp 1446—1464

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