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• Research PaperVolume 14, Issue 3pp 1233-1252

  PERK activation by SB202190 ameliorates amyloidogenesis via the TFEB-induced autophagy-lysosomal pathway

  Relevance score: 0.00

  Mihyang Do, Jeongmin Park, Yubing Chen, So-Young Rah, Thu-Hang Thi Nghiem, Jeong Heon Gong, Seong-A Ju, Byung-Sam Kim, Rina Yu, Jeong Woo Park, Stefan W. Ryter, Young-Joon Surh, Uh-Hyun Kim, Yeonsoo Joe, Hun Taeg Chung

  Keywords: amyloidogenesis, mitochondrial reactive oxygen species, PERK, transcription factor-EB, autophagy-lysosome pathway

  Published in Aging on February 15, 2022

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• Research PaperVolume 13, Issue 5pp 6634-6661

  CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice

  Relevance score: 0.00

  Fang Chen, Shunchang Fang, Yifeng Du, Arijit Ghosh, Miranda N. Reed, Yan Long, Vishnu Suppiramaniam, Susu Tang, Hao Hong

  Keywords: Alzheimer’s disease, cysteinyl leukotrienes receptor 1, cognition, amyloidogenesis, synaptic plasticity

  Published in Aging on February 11, 2021

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