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  • Research PaperVolume 8, Issue 3pp 484-505

    MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4

    Relevance score: 0.00

    Alexander Lang, Susanne Grether-Beck, Madhurendra Singh, Fabian Kuck, Sascha Jakob, Andreas Kefalas, Simone Altinoluk-Hambüchen, Nina Graffmann, Maren Schneider, Antje Lindecke, Heidi Brenden, Ingo Felsner, Hakima Ezzahoini, Alessandra Marini, Sandra Weinhold, Andrea Vierkötter, Julia Tigges, Stephan Schmidt, Kai Stühler, Karl Köhrer, Markus Uhrberg, Judith Haendeler, Jean Krutmann, Roland P. Piekorz

    Keywords: MicroRNA-15b/miR-15b, nuclear encoded mitochondrial genes, photoaging, reactive oxygen species/ROS, senescence, senescence associated secretory phenotype/SASP, SIRT4/Sirtuin 4, skin

    Published in Aging on February 26, 2016

  • Research PaperVolume 9, Issue 10pp 2163-2189

    SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy

    Relevance score: 0.00

    Alexander Lang, Ruchika Anand, Simone Altinoluk-Hambüchen, Hakima Ezzahoini, Anja Stefanski, Afshin Iram, Laura Bergmann, Jennifer Urbach, Philip Böhler, Jan Hänsel, Manuel Franke, Kai Stühler, Jean Krutmann, Jürgen Scheller, Björn Stork, Andreas S. Reichert, Roland P. Piekorz

    Keywords: Sirtuin-4/SIRT4, mitochondrial quality control, mitochondrial fusion/fission, mitophagy, OPA1, reactive oxygen species/ROS, senescence, fibroblast, aging

    Published in Aging on October 29, 2017

  • Research PaperVolume 5, Issue 11pp 835-849

    SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK

    Relevance score: 0.00

    Linh Ho, Allen Sam Titus, Kushal Kr Banerjee, Suji George, Wei Lin, Shaunak Deota, Asish K. Saha, Ken Nakamura, Philipp Gut, Eric Verdin, Ullas Kolthur-Seetharam

    Keywords: Sirt4, ANT2, AMPK, ATP, mitochondrial signaling

    Published in Aging on November 26, 2013