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• Research PaperVolume 13, Issue 14pp 18852-18869

  Regulation of the IGF1 signaling pathway is involved in idiopathic pulmonary fibrosis induced by alveolar epithelial cell senescence and core fucosylation

  Relevance score: 0.00

  Wei Sun, Xiaoyan Jing, Xiaoyu Yang, Hui Huang, Qun Luo, Shu Xia, Ping Wang, Na Wang, Qian Zhang, Jian Guo, Zuojun Xu

  Keywords: IPF, aging, alveolar epithelial cell, core fucosylation, IGF-1

  Published in Aging on July 30, 2021

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• Research PaperVolume 17, Issue 8pp 1999-2014

  AI-driven toolset for IPF and aging research associates lung fibrosis with accelerated aging

  Relevance score: 0.00

  Fedor Galkin, Shan Chen, Alex Aliper, Alex Zhavoronkov, Feng Ren

  Keywords: aging, IPF, generative AI, transformer, proteomics

  Published in Aging on August 8, 2025

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• Research PaperVolume 13, Issue 13pp 16922-16937

  A model of the aged lung epithelium in idiopathic pulmonary fibrosis

  Relevance score: 0.00

  Hoora Shaghaghi, Karina Cuevas-Mora, Rachel Para, Cara Tran, Willy Roque, Matthew J. Robertson, Ivan O. Rosas, Ross Summer, Freddy Romero

  Keywords: aging, IPF, mitochondria, proteostasis, epithelial cells

  Published in Aging on July 8, 2021

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• Research PaperVolume 12, Issue 7pp 5812-5831

  Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

  Relevance score: 0.00

  Qiqing Huang, Yan Chen, Shaoran Shen, Yuanyuan Wang, Liya Liu, Shuangshuang Wu, Wei Xu, Weihong Zhao, Mingyan Lin, Jianqing Wu

  Keywords: idiopathic pulmonary fibrosis (IPF), klotho (KL), weighted gene co-expression network analysis (WGCNA), precision-cut lung slices (PCLSs), pulmonary fibroblasts

  Published in Aging on April 3, 2020

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• Research PaperVolume 12, Issue 1pp 242-259

  Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation

  Relevance score: 0.00

  Xiang Chen, Hongyang Xu, Jiwei Hou, Hui Wang, Yi Zheng, Hui Li, Hourong Cai, Xiaodong Han, Jinghong Dai

  Keywords: idiopathic pulmonary fibrosis (IPF), epithelial cell senescence, pulmonary fibroblast activation, wnt/β-catenin signalling, nanog

  Published in Aging on December 31, 2019

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• Research PaperVolume 8, Issue 11pp 3091-3109

  The role of club cell phenoconversion and migration in idiopathic pulmonary fibrosis

  Relevance score: 0.00

  Jutaro Fukumoto, Ramani Soundararajan, Joseph Leung, Ruan Cox, Sanjay Mahendrasah, Neha Muthavarapu, Travis Herrin, Alexander Czachor, Lee C. Tan, Nima Hosseinian, Priyanshi Patel, Jayanthraj Gone, Mason T. Breitzig, Young Cho, Andrew J. Cooke, Lakshmi Galam, Venkata Ramireddy Narala, Yashwant Pathak, Richard F. Lockey, Narasaiah Kolliputi

  Keywords: club cells, idiopathic pulmonary fibrosis (IPF), Claudin10/Cldn10/Claudin-10, club cell secretory protein (CCSP), migration

  Published in Aging on November 29, 2016

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• Research PaperVolume 17, Issue 5pp 1298-1312

  The aspartate superpathway in gut microbiota-related metabolic pathways mediates immune cell protection against COPD and IPF: a Mendelian randomization analysis

  Relevance score: 0.00

  Lei Chen, Haoyan Chen, Qin Li, Jun Ma, Yanzhi Feng, Shenghua Zhang, Yu Han, Jie Pan, Mingjiong Zhang, Kai Sun, Shuangshuang Wu

  Keywords: Mendelian randomization, gut microbiota, idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), immune cells

  Published in Aging on May 15, 2025

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• Research PaperVolume 17, Issue 8pp 2189-2211

  Bleomycin promotes cellular senescence and activation of the cGAS-STING pathway without direct effect on fibrosis in an idiopathic pulmonary fibrosis model

  Relevance score: 0.00

  Yoko Miura, Nadia Milad, Akiho Takata, Satoshi Kanazawa

  Keywords: bleomycin, cGAS-STING, idiopathic pulmonary fibrosis (IPF), precision-cut lung slices (PCLS), senescence

  Published in Aging on August 28, 2025

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• Research PaperVolume 11, Issue 1pp 209-229

  Oxidative stress induces club cell proliferation and pulmonary fibrosis in Atp8b1 mutant mice

  Relevance score: 0.00

  Jutaro Fukumoto, Joseph Leung, Ruan Cox, Alexander Czachor, Prasanna Tamarapu Parthasarathy, Venu Lagishetty, Maria Mandry, Nima Hosseinian, Priyanshi Patel, Brittany Perry, Mason T. Breitzig, Matthew Alleyn, Athena Failla, Young Cho, Andrew J. Cooke, Lakshmi Galam, Ramani Soundararajan, Nirmal Sharma, Richard F. Lockey, Narasaiah Kolliputi

  Keywords: hyperoxia, Atp8b1, idiopathic pulmonary fibrosis (IPF), oxidative stress, club cells

  Published in Aging on January 13, 2019

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• Research PerspectiveVolume 17, Issue 8pp 1911-1928

  Age-related diseases as a testbed for anti-aging therapeutics: the case of idiopathic pulmonary fibrosis

  Relevance score: 0.00

  Alex Zhavoronkov, Dominika Wilczok, Feng Ren, Fedor Galkin

  Keywords: aging, drug development, idiopathic pulmonary fibrosis, ipf, scoring

  Published in Aging on August 16, 2025

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