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• Research PaperVolume 13, Issue 23pp 25055-25071

  IGFBP-6/sonic hedgehog/TLR4 signalling axis drives bone marrow fibrotic transformation in primary myelofibrosis

  Relevance score: 0.00

  Lucia Longhitano, Daniele Tibullo, Nunzio Vicario, Cesarina Giallongo, Enrico La Spina, Alessandra Romano, Sofia Lombardo, Marina Moretti, Francesco Masia, Anna Rita Daniela Coda, Santina Venuto, Paolo Fontana, Rosalba Parenti, Giovanni Li Volti, Michelino Di Rosa, Giuseppe A. Palumbo, Arcangelo Liso

  Keywords: IGFBP-6, myelofibrosis, mesenchymal stem cells, TLR4, MPNs

  Published in Aging on December 14, 2021

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• Research PaperVolume 12, Issue 16pp 16621-16646

  Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype

  Relevance score: 0.00

  Xiangyong Li, Qian Zhou, Shuangshuang Wang, Ping Wang, Juan Li, Zhiwei Xie, Chang Liu, Jie Wen, Xunwei Wu

  Keywords: Rho kinase inhibitor, Y-27632, senescence, IGFBP-5, dermal fibroblast

  Published in Aging on August 25, 2020

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