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• ReviewVolume 11, Issue 8pp 2488-2511

  A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair

  Relevance score: 0.00

  Eva Bártová, Soňa Legartová, Miroslav Dundr, Jana Suchánková

  Keywords: 53BP1, BRCA1, DNA damage, histone modifications, epigenetics

  Published in Aging on April 17, 2019

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• Research PaperVolume 9, Issue 9pp 1957-1970

  The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons

  Relevance score: 0.00

  Jose F. Moruno-Manchon, Edward C. Koellhoffer, Jayakrishnan Gopakumar, Shashank Hambarde, Nayun Kim, Louise D. McCullough, Andrey S. Tsvetkov

  Keywords: G-quadruplex, DNA damage, transcription, BRCA1, neurodegeneration

  Published in Aging on September 12, 2017

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• Research PaperVolume 13, Issue 24pp 25920-25930

  LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells

  Relevance score: 0.00

  Jiangdong Xiang, Lina Zhou, Yinyan He, Sufang Wu

  Keywords: LDH-A, PARP inhibitors, BRCA1, ovarian cancer, proliferation

  Published in Aging on December 16, 2021

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• Research PaperVolume 12, Issue 24pp 24872-24893

  Age-associated deficient recruitment of 53BP1 in G1 cells directs DNA double-strand break repair to BRCA1/CtIP-mediated DNA-end resection

  Relevance score: 0.00

  Teresa Anglada, Anna Genescà, Marta Martín

  Keywords: aging, double-strand break repair, 53BP1, BRCA1, non-homologous end-joining

  Published in Aging on December 27, 2020

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• Research PaperVolume 13, Issue 12pp 15917-15941

  Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization

  Relevance score: 0.00

  Natalie Tabor, Conelius Ngwa, Jeremie Mitteaux, Matthew D. Meyer, Jose F. Moruno-Manchon, Liang Zhu, Fudong Liu, David Monchaud, Louise D. McCullough, Andrey S. Tsvetkov

  Keywords: G-quadruplex, DNA damage, genomic instability, neurodegeneration, Brca1

  Published in Aging on June 19, 2021

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• EditorialVolume 9, Issue 9pp 1945-1946

  AURKA inhibition mimics BRCAness

  Relevance score: 0.00

  Jeff Hirst, Andrew K. Godwin

  Keywords: BRCAness, Aurora A kinase, PARP inhibition, synthetic lethality, non-homologous end joining

  Published in Aging on September 11, 2017