Interviews with Outstanding Authors 2022

Novel TRKB Agonists Activate TRKB and Downstream ERK and AKT Signaling

Dr. Ya-Jen Chiu from the Department of Life Science at National Taiwan Normal University in Taipei, discusses a paper she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, “Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity.”

DOI - https://doi.org/10.18632/aging.204306

Lotus Germ Extract Rejuvenates Fibroblasts Via Restoration of Disrupted Proteostasis

Dr. Takushi Namba, Associate Professor at Kochi University in Japan, discusses a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 19, entitled, “Lotus germ extract rejuvenates aging fibroblasts via restoration of disrupted proteostasis by the induction of autophagy.”

DOI - https://doi.org/10.18632/aging.204303

Psychological Factors Contribute to Biological Aging in Chinese Older Adults

Fedor Galkin, Scientific Director at Deep Longevity, Inc. in Hong Kong, discusses a research paper he co-authored that was published by Aging (Aging-US) as the cover for Volume 14, Issue 18, entitled, “Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults.”

DOI - https://doi.org/10.18632/aging.204264

Longevity & Aging Series (S1, E5): Dr. Amit Sharma

Dr. Amit Sharma, Group Lead from SENS Research Foundation, discusses a research paper he co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells.”

DOI - https://doi.org/10.18632/aging.203931

Epigenetic Clocks Association with Perceived Discrimination, Depressive Symptoms

Dr. May Beydoun from the Laboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, in Baltimore, MD, discusses a research paper she co-authored that was published by Aging (Aging-US) as the cover for Volume 14, Issue 13, entitled, “Epigenetic clocks and their association with trajectories in perceived discrimination and depressive symptoms among US middle-aged and older adults.”

DOI - https://doi.org/10.18632/aging.204150

Longevity & Aging Series (S1, E4): Drs. Carly Bobak, Cristian Coarfa and Andrew DiNardo

In episode 4 of the Longevity & Aging Series, Drs. Carly Bobak, Cristian Coarfa and Andrew DiNardo discuss a research paper they co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis.”

DOI - https://doi.org/10.18632/aging.203936

Longevity & Aging Series (S1, E3): Dr. Steve Horvath - Epigenetic Clocks

In episode 3 of the Longevity & Aging Series, Dr. Steve Horvath, Professor of Human Genetics and Biostatistics at UCLA, and Principal Investigator at Altos Labs, discusses the evolution of aging research and epigenetic clocks with host Dr. Brian Chen.

Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath

Longevity & Aging Series (S1, E2): Dr. Steve Horvath’s Special Collection in Aging

In the second installment of the Longevity & Aging Series, Dr. Steve Horvath revisits papers he co-authored that were published by Aging (Aging-US) and featured as a special collection of his research.

Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath

Biological Age in Diabetes and Precision Medicine

Dr. Cristina Aguayo-Mazzucato from Beta Cell Aging Lab, Joslin Diabetes Center, Harvard Medical School, discusses an editorial she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 11, entitled, “Biological age in diabetes and precision medicine.”

DOI - https://doi.org/10.18632/aging.204123

Facial Expression Recognition Predicts Neuropsychiatric Symptoms of Dementia

Dr. Liang-Kung Chen from the National Yang-Ming Chiao-Tung University, Taipei, Taiwan details a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 3, entitled, “Predicting neuropsychiatric symptoms of persons with dementia in a day care center using a facial expression recognition system.”

DOI - https://doi.org/10.18632/aging.203869

Longevity & Aging Series (S1, E1): Dr. Alex Zhavoronkov and Dr. Frank Pun

In the first episode of the Longevity & Aging Series, Drs. Alex Zhavoronkov and Frank Pun discuss, in detail, their recently published research paper, “Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine.”

DOI - https://doi.org/10.18632/aging.203960

The puzzling interplay between p53 and Sp1

Dr. Ariella Oppenheim from the Department of Hematology, Hebrew University Faculty of Medicine, Jerusalem, Israel, details an editorial she co-authored that was published by Aging (Aging-US) in Volume 9, Issue 5, entitled, “The puzzling interplay between p53 and Sp1.

DOI - https://doi.org/10.18632/aging.101238 (PDF download)

Full text - https://www.aging-us.com/article/101238

DNA Methylation-based Measures of Biological Age

Aging-US published "DNA methylation-based measures of biological age: meta-analysis predicting time to death" in 2016, which reported that estimates of biological age based on DNA methylation patterns, often referred to as "epigenetic age", "DNAm age", have been shown to be robust biomarkers of age in humans.

DOI - https://doi.org/10.18632/aging.101020

Epigenetic Age of the Pre-frontal Cortex

Aging-US published "Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning" in 2015, which reported that there is an urgent need to develop molecular biomarkers of brain age in order to advance our understanding of age related neurodegeneration.

DOI - https://doi.org/10.18632/aging.100864

Iron: An Underrated Factor in Aging

Dennis Mangan from MTOR LLC in Bakersfield, California details his theory article published by Aging (Aging-US), entitled, “Iron: an underrated factor in aging.”

DOI - https://doi.org/10.18632/aging.203612