Research Paper Volume 16, Issue 12 pp 10203—10215
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome
Figure 3. DS mice have a marked increase in lipid metabolism. PPARα, PPARγ, FATP5, and CTP2 are differently regulated in Ts2Cje livers. Representative histogram of the real-time PCR against PPARa (A), PPARg (B), FATP5 (C), and CTP2 (D) on the liver extract obtained from 12-months old Eu and Ts2Cje mice. GAPDH was used as housekeeping gene. Histograms are representative of four different experiments (*P ≤ 0.05).