Research Paper Volume 16, Issue 1 pp 431—444

Figure 6. Knockdown TBC1D1 affects the integrity of the F-actin. (A) Fluorescence microscopy was used to observe the morphological changes of F-actin cytoskeleton stained with phalloidin after transfection (Scale bar = 10 μm). (B) Detection of profilin, cofilin, P-LIMK1Thr508/P-LIMK2Thr505 and P-cofilinSer3 protein expression. (All data were presented as mean ± s.d. from three independent experiments (^*P < 0.05, ^**P < 0.01, ^***P < 0.005, ^****P < 0.001).