Figure 3. Immunohistochemistry results obtained from the HPA project database, expression of TBC1D1 across tissues and expression of TBC1D1 in glioma cell lines. (A) Protein expression of TBC1D1 in normal brain tissues. (B) Expression of TBC1D1 in low-grade glioma tissues. (C) Expression of TBC1D1 in high-grade glioma tissues. (D) Protein expression of TBC1D1 in glioma cell lines. (E) Knockdown of TBC1D1 by siRNA in T98 and LN229. (All data were presented as mean ± s.d. from three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001).