Research Paper Volume 15, Issue 21 pp 12330—12368

A robust six-gene prognostic signature based on two prognostic subtypes constructed by chromatin regulators is correlated with immunological features and therapeutic response in lung adenocarcinoma

class="figure-viewer-img"

Figure 14. Expression of prognostic genes and underlying prognostic mechanism. (A) Expression of prognostic genes. CPS1 and TPSB2 genes were lowly expressed in LUAD tissues by a quantitative real-time PCR method. (B) Survival curve. The high expression of CIT gene resulted in a better overall survival rate in patients with lung adenocarcinoma. (C) Prognostic results and potential prognostic mechanism based on prognostic chromatin regulators. According to the prognostic results and existing literature, the potential prognostic mechanism was delineated.