Research Paper Volume 15, Issue 20 pp 11092—11113
Identification and validation of a cancer-associated fibroblasts-related scoring system to predict prognosis and immune landscape in hepatocellular carcinoma through integrated analysis of single-cell and bulk RNA-sequencing
Figure 3. Identification of CAFs-associated genes in HCC. (A) A total of 311 DEGs and 3683 CAFs-related genes were overlapped to obtain 135 intersecting genes. (B) Protein interaction network map of the 135 intersecting genes. (C) A total of 30 prognosis-associated genes were obtained using uni-Cox regression. (D) The log (lambda) sequence plot of CAFs-related genes using the LASSO algorithm. (E) LASSO coefficient profiles of the eleven CAFs-associated genes.