Research Paper Volume 15, Issue 17 pp 9182—9192
KIF18A improves migration and invasion of colorectal cancer (CRC) cells through inhibiting PTEN signaling
Figure 1. The expression of KIF18A in colorectal cancer tissues. (A, B) The transcriptional level (FPKM value) of KIF18A in pan-cancer tissues from the TCGA database. (Abbreviations: ACC: Adrenocortical Cancer; BRCA: Breast Invasive Carcinoma (Breast Cancer); CHOL: Cholangiocarcinoma (Bile Duct Cancer); DLBC: Diffuse Large B-Cell Lymphoma; GMB: Glioblastoma Multiforme (Brain Cancer); KICH: Kidney Chromophobe; KIRP: Kidney Renal Papillary Cell Carcinoma; LGG: Lower Grade Glioma; LUAD: Lung Adenocarcinoma; OV: Ovarian Serous Cystadenocarcinoma (Ovarian Cancer); PCPG: Pheochromocytoma and Paraganglioma; READ: Rectum Adenocarcinoma; SKCM: Skin Cutaneous Melanoma; TGCT: Testicular Germ Cell Tumors; THYM: Thymoma; UCS: Uterine Carcinosarcoma)). (C) The transcriptional level (FPKM value) of KIF18A in CRC and normal samples from the TCGA database. (COADREAD: Colon and Rectal Cancer). (D) The heatmap of genes involved in the cell adhesion and migration in shKIF18A-SW480 cells.