Figure 2. Establishment and validation of coagulation-related risk signature. (A) Least absolute shrinkage and selection operator cox analysis of the DEGs. (B) Partial likelihood deviance coefficient profiles. (C) Forest map of the variables contained in the risk signature. (D) Risk factor diagram, ROC curve and KM curve of the risk signature in the training set. The AUC of ROC curve is 0.76, while HR of KM curve is 3.28, p < 0.001. (E) Risk factor diagram, ROC curve and KM curve of the risk signature in the internal test set. The AUC of ROC curve is 0.74, while HR of KM curve is 3.5, p < 0.001.