Research Paper Volume 15, Issue 10 pp 4304—4318
Integrated network findings reveal ubiquitin-specific protease 44 overexpression suppresses tumorigenicity of liver cancer
Figure 1. Low expression of USP44 is a prognostic factor in hepatocellular carcinoma (HCC). (A) USP44 expression in 40 pairs of HCC nontumoral (NT) and tumoral (T) tissues. USP44 expression was lower in tumoral tissues than in nontumoral tissues (p < 0.0001). (B) Correlation between USP44 expression and survival rate of patients with HCC. Low USP44 expression was related to shorter overall survival (p = 0.047) and disease-free survival (p = 0.019) in patients with HCC. The x-axis indicates survival time in months. The y-axis indicates survival probability. The log-rank p < 0.05 indicates that USP44 expression is significantly associated with prognosis in HCC.