Figure 4. Screening of the prognostic genes in the TCGA dataset. (A) Univariate Cox regression analysis of 16 hub genes in the TCGA dataset. (B) Partial likelihood deviance of different numbers of variables revealed by the LASSO regression model. (C) LASSO coefficient profiles of the selected hub genes. (D) Kaplan-Meier curves displayed highly expressed genes screened out by LASSO were significantly related to poor prognosis in the TCGA dataset.