Research Paper Volume 11, Issue 9 pp 2762—2786

MiR-191 inhibit angiogenesis after acute ischemic stroke targeting VEZF1

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Figure 8. Inhibition of miR-191 reduced infarction volume of MCAO rats after the injection of miR-191 antagomir compared to NC antagomir and blank control. Relative miR-191 levels in (A) plasma and (B) IBZ (n =4 per group); (C) Real-time PCR analysis of VEZF1 expression in IBZ (n =4 per group); (D, E) Western blot analysis of VEZF1 expression in IBZ (n =4 per group); (F, G) Relative infarct volume of MCAO rats (n =4 per group). Means ± SEM. * P< 0.05,** P< 0.01 vs. NC antagomir.