Research Paper Volume 4, Issue 9 pp 636—647
Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging
Figure 3. Reactive oxygen species (ROS) and ATP levels in wild type and mutant C. elegans strains. (A) ROS levels in whole body of 7-day adult old worms (post-larval L4 stage) detected with dichlorofluorescein. Data are expressed as units of fluorescence per micrograms of proteins. (Unpaired Student's t-test; *P = 0.0442 vs. wild type; **P = 0.0008 vs. wild type). (B) ATP levels in whole body of 7-day old adult worms (post-larval L4 stage). (Unpaired Student's t-test; *P = 0.0410 vs. wild type; **P = 0.0137 vs. wild type). Data are expressed as units of fluorescence per micrograms of proteins. Twenty-five worms of each genotype were collected for the ROS or ATP measurements. Experiments were performed with three independent pools of animals.