Correction|Volume 16, Issue 20|pp 13172—13173

Correction for: Chronic alcohol exposure promotes HCC stemness and metastasis through β-catenin/miR-22-3p/TET2 axis

Danlei Chen^1,², Yan Yan¹, Xinyi Wang^1,³, Suzhi Li¹, Yan Liu¹, Dandan Yu¹, Yongjing He¹, Ruiqing Deng¹, Yakun Liu¹, Mei Xu⁴, Jia Luo⁵, Hongjun Gao^1,³, Siying Wang¹

¹School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, Anhui, China
²The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, Anhui, China
³Department of Pulmonary Oncology, The Fifth Medical Center of Chinese PLA General Hospital, Fengtai, Beijing 100071, China
⁴Department of Pharmacology and Nutritional Sciences, University of Kentucky, College of Medicine, Lexington, KY 40536, USA
⁵Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA

Received: May 3, 2022Accepted: October 28, 2024

https://doi.org/10.18632/aging.206147

Copyright: © 2024 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

This article has been corrected: The authors would like to correct the invasion assay image of the SMMC-7721 cells control group in Figure 3L. It was found that this image overlaps to a small degree the image of the SMMC-7721 miR-22-3p inhibitor group. This was the result of an unintentional error in the naming of the image file for the miR-22-3p inhibitor group. The authors provided the original data and corrected this error with an image from the original sets of experiments. This error does not affect the study’s conclusions, because the analysis was conducted using the correct datasets from repeated experiments.

The corrected version of Figure 3 is provided below.

Figure 3.

Effects of miR-22-3p on stemness and metastasis of HCC cells. (A) Tumorspheres formation ability of HCC cells in control, negative-control, miR-22-3p mimic and inhibitor groups. (B) The tumorspheres were quantified. ^*P < 0.05. (C, D) Population of EPCAM- positive HCC cells in control, negative-control, miR-22-3p mimic and inhibitor groups. ^*P < 0.05. (E, F) Population of CD133- positive HCC cells in control, negative-control, miR-22-3p mimic and inhibitor groups. ^*P < 0.05. (G) The representative images of tumors taken from athymic mice inoculated with SMMC-7721 cells in control, negative-control, miR-22-3p mimic and inhibitor groups are shown. (H) The growth of tumor was calculated. Each group consisted of five mice. ^*P < 0.05. (I) The tumor weight was quantified. Each group consisted of five mice. ^*P < 0.05. (J) Representative image showing the migration of HCC cells in control, negative-control, miR-22-3p mimic and inhibitor groups. (K) The migrated cells were quantified. ^*P < 0.05, n = 3. (L) Representative image showing the invasion of HCC cells in control, negative-control, miR-22-3p mimic and inhibitor groups. (M) The invaded cells were quantified. ^*P < 0.05, n = 3.