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Research Paper|Volume 11, Issue 13|pp 4438—4445

Fasting blood glucose level and hypertension risk in aging benign prostatic hyperplasia patients

Hao Zi1,2,3, Xue-Jun Wang4, Ming-Juan Zhao2,3,5, Qiao Huang2, Xing-Huan Wang1,2, Xian-Tao Zeng1,2
  • 1Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China
  • 2Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China
  • 3Center for Evidence-Based Medicine, Institute of Evidence-Based Medicine and Knowledge Translation, Henan University, Kaifeng, Henan 475000, China
  • 4Department of Emergency, Beijing Electric Power Hospital, Beijing 100073, China
  • 5Department of Cardiology, The First Affiliated Hospital of Henan University, Kaifeng, Henan 475000, China
Received: March 9, 2019Accepted: June 24, 2019Published: July 3, 2019
https://doi.org/10.18632/aging.102061

Copyright: Zi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Evidence suggests there maybe an association among abnormal fasting blood glucose, hypertension and benign prostatic hyperplasia. In this study, we investigated whether abnormal fasting blood glucose correlates with hypertension in aging benign prostatic hyperplasia patients. Ultimately, 612 benign prostatic hyperplasia patients, including 230 hypertensive patients and 382 normotensive patients, were included. Univariate and multivariate logistic regression analyses were used to evaluate the associations. The results indicated that neither impaired fasting glucose/high risk of type 2 diabetes mellitus nor high risk of type 2 diabetes mellitus were associated with an increased risk of hypertension. When patients were stratified based on the severity of their hypertension, similar results were obtained (all P> 0.05). After adjusting for confounding factors, the nonsignificant tendencies for high risk of type 2 diabetes mellitus and impaired fasting glucose/high risk of type 2 diabetes mellitus to associate with hypertension persisted (all P> 0.05). Unlike earlier studies, the present study suggests that the level of fasting blood glucose may not be significantly related to hypertension in aging patients with benign prostatic hyperplasia.