Alexey Moskalev1,Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia10,Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia27,Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia38Vavilov Institute of General Genetics RAS, Moscow, Russia, Vladimir Anisimov2Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia, Aleksander Aliper3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA, Artem Artemov3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA, Khusru Asadullah4Bayer Global Drug Discovery, Berlin, Germany, Daniel Belsky5Social Science Research Institute, Duke University, Durham, NC 27708, USA, Ancha Baranova6School of Systems Biology, George Mason University, VA 20110, USA, Aubrey de Grey7SENS Research Foundation, 1 Beaconsfield Terrace, Cambridge, CB2 3EH, UK, Vishwa Deep Dixit8Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA, Edouard Debonneuil9ActuRx, 92330 Sceaux, France, Eugenia Dobrovolskaya10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia, Peter Fedichev11Gero Limited, International Commerce Center, Kowloon, Hong Kong, Alexander Fedintsev1Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia, Vadim Fraifeld12The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer-Sheva, Israel, Claudio Franceschi13Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy, Rosie Freer14Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK, Tamas Fülöp15Department of Medicine, Research Center on Aging, Graduate Program in Immunology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada, Jerome Feige16Nestlé Institute of Health Sciences, EPFL Innovation Park, 1015 Lausanne, Switzerland, David Gems17Institute of Healthy Ageing, and Department of Genetics, Evolution and Environment, University College London, London, UK, Vadim Gladyshev18Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA, Vera Gorbunova19Department of Biology, University of Rochester, Rochester, NY 14627, USA, Irina Irincheeva20Nutrition and Metabolic Health Group, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland, Sibylle Jager21Open Research Department, L’Oreal, 93600 Aulnay-sous-Bois, France, S. Michal Jazwinski22Tulane Center for Aging and Department of Medicine, Tulane University Health Sciences Center, SL-12, New Orleans, LA 70112, USA, Matt Kaeberlein23Department of Pathology, University of Washington, Seattle, WA 98195, USA, Brian Kennedy24Buck Institute for Research on Aging, Novato, CA 94945, USA, Daria Khaltourina25Department of the Integrated Prevention Programs, Federal State Institution "National Research Center for Preventive Medicine" of the Ministry of Healthcare of the Russian Federation, 101990, Moscow, Russia, Igor Kovalchuk26Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, T1K 3M4, Canada, Olga Kovalchuk26Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, T1K 3M4, Canada, Sergey Kozin27Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia, Alexander Kulminski5Social Science Research Institute, Duke University, Durham, NC 27708, USA, Ekaterina Lashmanova1Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia, Ksenia Lezhnina3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA, Guang-Hui Liu8Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA, Valter Longo29Longevity Institute and Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA, Polina Mamoshina3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA, Alexander Maslov30Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Joao Pedro de Magalhaes31Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK, James Mitchell32Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA, Arnold Mitnitski33Department of Medicine, Dalhousie University, Centre for Health Care of the Elderly-Suite 1305, 5955 Veterans' Memorial Lane Halifax, Nova Scotia, B3H 2E1 Canada, Yuri Nikolsky34Biomedical Cluster, Skolkovo Foundation, Skolkovo, Russia, Ivan Ozerov3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA, Elena Pasyukova35Institute of Molecular Genetics of Russian Academy of Sciences, Moscow, Russia, Darya Peregudova10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia, Vasily Popov36Voronezh State University, Voronezh, Russia, Ekaterina Proshkina10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia, Evgeny Putin37Computer Technologies Lab, ITMO University, St. Petersburg 197101, Russia, Evgeny Rogaev38Vavilov Institute of General Genetics RAS, Moscow, Russia, Blanka Rogina39Institute for Systems Genomics, School of Medicine, University of Connecticut Health, Farmington, CT 06030, USA, Jane Schastnaya3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA, Andrey Seluanov19Department of Biology, University of Rochester, Rochester, NY 14627, USA, Mikhail Shaposhnikov10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia, Andreas Simm40Centre of Medical Basic Research, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany, Vladimir Skulachev41Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia, Maxim Skulachev41Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia, Ilya Solovev10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia, Stephen Spindler42Department of Biochemistry, University of California at Riverside, Riverside, CA 92521, USA, Natalia Stefanova43Institute of Cytology and Genetics of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia, Yousin Suh30Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Andrew Swick44Life Extension, Ft. Lauderdale, FL 33308, USA, John Tower45Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA, Andrei V. Gudkov46Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA, Jan Vijg30Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Andrey Voronkov1Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia, Michael West47BioTime, Inc., Alameda, CA 94501, USA, Wolfgang Wagner48Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, RWTH Aachen University, Aachen, Germany, Anatoliy Yashin5Social Science Research Institute, Duke University, Durham, NC 27708, USA, Nadezhda Zemskaya10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia, Zhaxybay Zhumadilov49Center for Life Sciences Nazarbayev University, Astana, Kazakhstan, Alex Zhavoronkov3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA
- 1Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia
- 2Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia
- 3Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA
- 4Bayer Global Drug Discovery, Berlin, Germany
- 5Social Science Research Institute, Duke University, Durham, NC 27708, USA
- 6School of Systems Biology, George Mason University, VA 20110, USA
- 7SENS Research Foundation, 1 Beaconsfield Terrace, Cambridge, CB2 3EH, UK
- 8Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA
- 9ActuRx, 92330 Sceaux, France
- 10Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia
- 11Gero Limited, International Commerce Center, Kowloon, Hong Kong
- 12The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer-Sheva, Israel
- 13Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy
- 14Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK
- 15Department of Medicine, Research Center on Aging, Graduate Program in Immunology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada
- 16Nestlé Institute of Health Sciences, EPFL Innovation Park, 1015 Lausanne, Switzerland
- 17Institute of Healthy Ageing, and Department of Genetics, Evolution and Environment, University College London, London, UK
- 18Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
- 19Department of Biology, University of Rochester, Rochester, NY 14627, USA
- 20Nutrition and Metabolic Health Group, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland
- 21Open Research Department, L’Oreal, 93600 Aulnay-sous-Bois, France
- 22Tulane Center for Aging and Department of Medicine, Tulane University Health Sciences Center, SL-12, New Orleans, LA 70112, USA
- 23Department of Pathology, University of Washington, Seattle, WA 98195, USA
- 24Buck Institute for Research on Aging, Novato, CA 94945, USA
- 25Department of the Integrated Prevention Programs, Federal State Institution "National Research Center for Preventive Medicine" of the Ministry of Healthcare of the Russian Federation, 101990, Moscow, Russia
- 26Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, T1K 3M4, Canada
- 27Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia
- 28National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
- 29Longevity Institute and Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA
- 30Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- 31Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK
- 32Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
- 33Department of Medicine, Dalhousie University, Centre for Health Care of the Elderly-Suite 1305, 5955 Veterans' Memorial Lane Halifax, Nova Scotia, B3H 2E1 Canada
- 34Biomedical Cluster, Skolkovo Foundation, Skolkovo, Russia
- 35Institute of Molecular Genetics of Russian Academy of Sciences, Moscow, Russia
- 36Voronezh State University, Voronezh, Russia
- 37Computer Technologies Lab, ITMO University, St. Petersburg 197101, Russia
- 38Vavilov Institute of General Genetics RAS, Moscow, Russia
- 39Institute for Systems Genomics, School of Medicine, University of Connecticut Health, Farmington, CT 06030, USA
- 40Centre of Medical Basic Research, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany
- 41Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia
- 42Department of Biochemistry, University of California at Riverside, Riverside, CA 92521, USA
- 43Institute of Cytology and Genetics of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
- 44Life Extension, Ft. Lauderdale, FL 33308, USA
- 45Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA
- 46Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
- 47BioTime, Inc., Alameda, CA 94501, USA
- 48Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, RWTH Aachen University, Aachen, Germany
- 49Center for Life Sciences Nazarbayev University, Astana, Kazakhstan
