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Special Collection on Longevity and Rapamycin


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Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)

Corinna Ross, Adam Salmon, Randy Strong, Elizabeth Fernandez, Marty Javors, Arlan Richardson, Suzette Tardif,
https://doi.org/10.18632/aging.100843 pp 964—973
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Rapamycin-induced metabolic defects are reversible in both lean and obese mice

Yuhong Liu, Vivian Diaz, Elizabeth Fernandez, Randy Strong, Lan Ye, Joseph A. Baur, Dudley W. Lamming, Arlan Richardson, Adam B. Salmon,
https://doi.org/10.18632/aging.100688 pp 742—754
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Target of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration

Sahar Emran, Mingyao Yang, Xiaoli He, Jelle Zandveld, Matthew D. W. Piper,
https://doi.org/10.18632/aging.100665 pp 390—398
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Rapamycin in preventive (very low) doses

Roman V. Kondratov, Anna A. Kondratova,
https://doi.org/10.18632/aging.100645 pp 158—159
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Immunostimulatory activity of lifespan-extending agents

José Manuel Bravo-San Pedro, Laura Senovilla,
https://doi.org/10.18632/aging.100619 pp 793—801
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Rapamycin extends life- and health span because it slows aging

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100591 pp 592—598
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Prolonged Rapamycin treatment led to beneficial metabolic switch

Yimin Fang, Andrzej Bartke,
https://doi.org/10.18632/aging.100554 pp 328—329
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Rapamycin extends life span of Rb1+/− mice by inhibiting neuroendocrine tumors

Carolina B. Livi, Rulon L. Hardman, Barbara A. Christy, Sherry G. Dodds, Diane Jones, Charnae Williams, Randy Strong, Alex Bokov, Martin A. Javors, Yuji Ikeno, Gene Hubbard, Paul Hasty, Zelton Dave Sharp,
https://doi.org/10.18632/aging.100533 pp 100—110
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Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency

Lawrence A. Donehower,
https://doi.org/10.18632/aging.100494 pp 660—661
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Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

Elena A. Komarova, Marina P. Antoch, Liliya R. Novototskaya, Olga B. Chernova, Geraldine Paszkiewicz, Olga V. Leontieva, Mikhail V. Blagosklonny, Andrei V. Gudkov,
https://doi.org/10.18632/aging.100498 pp 709—714
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New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis

Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch,
https://doi.org/10.18632/aging.100496 pp 715—722
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How to save Medicare: the anti-aging remedy

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100479 pp 547—552
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Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100461 pp 350—358
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Rapamycin increases oxidative stress response gene expression in adult stem cells

Amber E. Kofman, Margeaux R. McGraw, Christopher J. Payne,
https://doi.org/10.18632/aging.100451 pp 279—289
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The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae

Cheol Woong Ha, Won-Ki Huh,
https://doi.org/10.18632/aging.100299 pp 319—324
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Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex

Philippe Major,
https://doi.org/10.18632/aging.100298 pp 189—191
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Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level

Alexander A. Goldberg, Pavlo Kyryakov, Simon D. Bourque, Vladimir I. Titorenko,
https://doi.org/10.18632/aging.100186 pp 461—470
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Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

Alexander A. Goldberg, Vincent R. Richard, Pavlo Kyryakov, Simon D. Bourque, Adam Beach, Michelle T. Burstein, Anastasia Glebov, Olivia Koupaki, Tatiana Boukh-Viner, Christopher Gregg, Mylène Juneau, Ann M. English, David Y. Thomas, Vladimir I. Titorenko,
https://doi.org/10.18632/aging.100168 pp 393—414
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Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100149 pp 265—273
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Why human lifespan is rapidly increasing: solving "longevity riddle" with "revealed-slow-aging" hypothesis

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100139 pp 177—182
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Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

Yong Pan, Gerald S. Shadel,
https://doi.org/10.18632/aging.100016 pp 131—145
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Macronutrient balance and lifespan

Stephen J. Simpson, David Raubenheimer,
https://doi.org/10.18632/aging.100098 pp 875—880
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The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1

Gino Heeren, Mark Rinnerthaler, Peter Laun, Phyllis von Seyerl, Sonja Kössler, Harald Klinger, Stefanie Jarolim, Birgit Simon-Nobbe, Matthias Hager, Christoph Schüller, Didac Carmona-Gutierrez, Lore Breitenbach-Koller, Christoph Mück, Pidder Jansen-Dürr, Alfredo Criollo, Guido Kroemer, Frank Madeo, Michael Breitenbach,
https://doi.org/10.18632/aging.100065 pp 622—636
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