Figure 4.Pathway gene expression during aging in mouse and human tissues. Heatmaps display normalized logCPM expression of pathway genes. Differential expression in mouse samples was determined using edgeR with Benjamini–Hochberg correction (FDR < 0.1). In the human dataset, statistical significance was defined as p < 0.05 (unadjusted) due to high biological heterogeneity and limited sample size.