Research Paper Volume 16, Issue 14 pp 11339—11358
PART1 facilitates tumorigenesis and inhibits ferroptosis by regulating the miR-490-3p/SLC7A11 axis in hepatocellular carcinoma
Figure 4. PART1 protects HCC cells against erastin-induced ferroptosis. (A) GSEA of the WP_Ferroptosis gene set was performed in HCC patients with different PART1 expression levels. (B) The relative levels of MDA in HCCLM3 and Huh7 cells transfected with siRNA-PART1.1 and -PART1.3 in the erastin-induced ferroptosis assay. (C) The relative levels of iron in HCCLM3 and Huh7 cells transfected with siRNA-PART1.1 and -PART1.3 in the erastin-induced ferroptosis assay. **p < 0.01, ***p < 0.001.