Research Paper Volume 16, Issue 14 pp 11339—11358
PART1 facilitates tumorigenesis and inhibits ferroptosis by regulating the miR-490-3p/SLC7A11 axis in hepatocellular carcinoma
Figure 3. Downregulation of PART1 inhibits migration, invasion, and metastasis of HCC cells. (A) The migration and invasion were examined by wound healing assay in HCCLM3 and Huh7 cells transfected with siRNA-PART1.1 and -PART1.3. (B, C) The migration and invasion were illustrated by Transwell assay (40 × objective lens) in HCCLM3 and Huh7 cells transfected with siRNA-PART1.1 and -PART1.3. (D) The expression of apoptosis and EMT-related proteins (E-cadherin, vimentin, and N-cadherin) was detected by Western blotting. *p < 0.05, **p < 0.01, ***p < 0.001.