Research Paper Volume 16, Issue 13 pp 11027—11061

Characteristics of auto-quantified tumor-infiltrating lymphocytes and the prognostic value in adenocarcinoma of the esophagogastric junction, gastric adenocarcinoma, and esophageal squamous cell carcinoma

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Figure 1. Establishment and verifications of the cell training set in AEGJ. (A) Example images of the three classes used in the classifier: cancer cells, lymphocytes, and stromal cells. (B) Cell proportions obtained by automated image analysis were compared to pathologists’ counts for a total of 10,000 single cells in a representative set of 20 tissue samples within AEGJ. (C) TILs proportions versus manual grading for AEGJ TIL infiltration in random one-third samples.