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Figure 6. dCAFs were related to platinum resistance in OC patients. (A) Representative plots of Masson staining and Sinus rose BB staining in platinum-sensitive and -resistant OC cohorts (scale bar: 50 μm). The collagen fiber density was identified by AOD. (B) Elastic coefficient (kPa) and representative ultrasound elastography images of OC patients with platinum treatment. (C) Representative IHC staining of POSTN and SFRP2 in platinum-sensitive and -resistant cohorts (scale bar: 50 μm). The expression level of POSTN and SFRP2 was identified by AOD. (D) Quantitative analysis of IC₅₀ of OVCAR3 with cisplatin treatment for 24 hours in the presence or absence of recombinant POSTN (1 μg/ml) or recombinant SFRP2 (1 μg/ml). (***p < 0.001, **p < 0.01, *p < 0.05).