Research Paper Volume 16, Issue 12 pp 10636—10656
Comprehensive single-cell and bulk RNA-seq analyses reveal a novel CD8+ T cell-associated prognostic signature in ovarian cancer
Figure 2. Construction and validation of a prognostic model based on specific CD8+ T cell markers in ovarian cancer. (A) Coefficient profiles in the LASSO regression model. (B) Cross-validation for tuning parameter selection in the LASSO regression. (C) Kaplan-Meier survival analysis was performed on the relationship between the risk score and OS using the TCGA training cohort. (D) The rank of risk score in the TCGA training cohort. (E) Survival status in the TCGA training cohort. (F) Time-dependent ROC curve analysis of the prognostic model (1, 2, 3, and 5 years) in the TCGA training cohort. (G) Kaplan-Meier survival analysis was performed on the relationship between the risk score and OS using the GSE30161 validation cohort. (H) The rank of risk score in the GSE30161 validation cohort. (I) Survival status in the GSE30161 validation cohort. (J) Time-dependent ROC curve analysis of the prognostic model (1, 2, 3, and 5 years) in the GSE30161 validation cohort.