Research Paper Volume 16, Issue 12 pp 10615—10635
Identification and validation of key genes in gastric cancer: insights from in silico analysis, clinical samples, and functional assays
Figure 11. Targeted bisulfite sequencing-based methylation level exploration and receiver operating characteristic (ROC) curve analysis of the hub genes, including COL1A1, COL1A2, COL3A1, and FN1 in Pakistani gastric cancer (GC) patients and normal controls. (A) Beta value-based methylation analysis of COL1A1, COL1A2, COL3A1, and FN1 in Pakistani GC patients and control samples, and (B) targeted bisulfite sequencing-based ROC curves of the COL1A1, COL1A2, COL3A1, and FN1 methylation level. P-value < 0.05.