Research Paper Volume 16, Issue 12 pp 10446—10461
Notoginsenoside R1 (NGR1) regulates the AGE-RAGE signaling pathway by inhibiting RUNX2 expression to accelerate ferroptosis in breast cancer cells
Figure 7. NGR1 inhibits AGE-RAGE pathway activation by down-regulating RUNX2. (A, B) Changes in the expression of AGE, RAGE, and RUNX2 proteins in MDA-MB-231 and SK-BR-3 cells were detected by Western blot assay. (* P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001).