Research Paper Volume 16, Issue 12 pp 10435—10445

Inhibition of non-small cell lung cancer metastasis by knocking down APE1 through regulating myeloid-derived suppressor cells-induced immune disorders

class="figure-viewer-img"

Figure 5. APE1 knockdown enhances anti-tumor immunity in subcutaneous A549 mouse model. (A) PCA analysis; (B, C) Analysis of differential expression genes; (D) KEGG pathway analysis; (E) Validation of MDSC-related cytokine expression by RT-PCR; (F) Summary of transcriptome analysis. **p < 0.01, ***p < 0.001.