Figure 5. The association between TIICs and VPRS. (A) Differential analysis of 22 kinds of TIICs in the low and high-risk groups in training sets. (B, C) Spearman’s correlation analysis for risk score and M1 and M2 macrophages in TCGA cohorts, each dot plot represents a subject, and the correlation is fitted into a straight blue line. (D) Differential analysis of 22 kinds of TIICs in the low and high-risk groups invalidation sets. (E, F) Spearman’s correlation analysis for risk score and M1 and M2 macrophages in ICGC cohorts, each dot plot represents a subject, and the correlation is fitted into a straight blue line. R, rho; ***p < 0.001, **p < 0.001, *p < 0.05.