Figure 5 — MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation

Research Paper|Volume 16, Issue 12|pp. 10239–10251

MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation

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Figure 5.Summary schematic of this study: miR-33a-5p mediates the crosstalk between inflammatory factor accumulation in stored blood and macrophages. This contributed to the activation of M1 macrophages through the PPARα/ACC2/AMPK/CPT-1a pathway.