Research Paper Volume 16, Issue 12 pp 10239—10251
MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation
Figure 5. Summary schematic of this study: miR-33a-5p mediates the crosstalk between inflammatory factor accumulation in stored blood and macrophages. This contributed to the activation of M1 macrophages through the PPARα/ACC2/AMPK/CPT-1a pathway.