Research Paper Volume 16, Issue 11 pp 9990—10003
Analysis and experimental validation of genes and their transcription factor prediction in contused rat spinal cord at the intermediate phase
Figure 5. TFAM might regulate gene transcription of IGF1 and effected alterations in the function recovery of rats after SCI. (A) IGF1 and TFAM was significantly down-regulated after SCI. (B) BBB scale was performed for assessing motor recovery of rats hind limbs after SCI. (C) Gait footprints were recorded at 35 days post-injection and there were significant improvement in the TFAM-overexpression group in average speed and cadence (steps/second) compared with SCI group.