Research Paper Volume 16, Issue 11 pp 9813—9823

Figure 1. Visual function and DNA damage in the mice model of HS-induced glaucoma. (A) IOP was dynamically monitored weekly using a tonometer for 5 weeks. (B) Visual acuity was measured by monitoring the spatial frequency threshold of each animal responding to the rotating grating at a speed of 12°/s. (C) Contrast sensitivity was determined by taking the reciprocal of the contrast threshold until the mouse without any response. (D) DNA damage of the mice's retina at the end of the 5^th week was detected by immunofluorescence. *p<0.05 vs Sham. n=5 of each group.